ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48. - Wikidata - wikimedia - TriplyDB

ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48.

ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48.

http://www.wikidata.org/entity/Q30573228

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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential The Immunogenetics of Autoimmune Cholestasis Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.ORMDL3 is associated with airway remodeling in asthma via the ERK/MMP-9 pathway Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model Sphingolipid metabolites in inflammatory disease.The Association of GSDMB and ORMDL3 Gene Polymorphisms With Asthma: A Meta-Analysis An ADAM33 polymorphism associates with progression of preschool wheeze into childhood asthma: a prospective case-control study with replication in a birth cohort study.ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy.Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice Genetics of allergy and allergic sensitization: common variants, rare mutations Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21 ORMDL3 contributes to the risk of atherosclerosis in Chinese Han population and mediates oxidized low-density lipoprotein-induced autophagy in endothelial cells.Airway reactivity and sphingolipids-implications for childhood asthma Roles of CD48 in regulating immunity and tolerance.Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci.Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells.Genetic risk factors for the development of allergic disease identified by genome-wide association Histone Modifications and Asthma. The Interface of the Epigenetic and Genetic Landscapes.ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.The role of ORMDL proteins, guardians of cellular sphingolipids, in asthma.Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up.Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.sCD48 is anti-inflammatory in Staphylococcus aureus Enterotoxin B-induced eosinophilic inflammation.CD48 on blood leukocytes and in serum of asthma patients varies with severity.Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide.Elevated fractional exhaled nitric oxide and blood eosinophil counts are associated with a 17q21 asthma risk allele in adult subjects.Association of ORMDL3 with rhinovirus-induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes.ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.Lessons from ten years of genome-wide association studies of asthma.A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle.Evaluation of Soluble CD48 Levels in Patients with Allergic and Nonallergic Asthma in Relation to Markers of Type 2 and Non-Type 2 Immunity: An Observational Study

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ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48.

http://www.wikidata.org/entity/Q30573228

description

2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年学术文章

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2013年學術文章

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name

ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

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ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

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ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

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ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

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ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

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ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

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ORMDL3 promotes eosinophil tra ...... ulation of integrins and CD48.

@en

P2093

Amrita Rao

http://www.w3.org/2001/XMLSchema#string

Bit Na Kang

http://www.w3.org/2001/XMLSchema#string

Nooshin S Bahaie

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P Sriramarao

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Savita P Rao

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Sung Gil Ha

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Xiao Na Ge

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P2860

Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6

ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins

Orm family proteins mediate sphingolipid homeostasis

Cloning, expression, and characterization of the human eosinophil eotaxin receptor

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

Cell migration: integrating signals from front to back

Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells

Genome-wide association study to identify genetic determinants of severe asthma.

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

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10.1038/NCOMMS3479

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1016010434

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3940275

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