Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart. - Wikidata - wikimedia - TriplyDB

Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.

Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.

http://www.wikidata.org/entity/Q36151679

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Elevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac function PPARs and the cardiovascular system PPARs: Protectors or Opponents of Myocardial Function?Zebrafish as a Model to Study the Role of Peroxisome Proliferating-Activated Receptors in Adipogenesis and Obesity Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications--a review Alteration of energy substrates and ROS production in diabetic cardiomyopathy PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease Mitochondrial function in vascular endothelial cell in diabetes Sexually dimorphic adaptation of cardiac function: roles of epoxyeicosatrienoic acid and peroxisome proliferator-activated receptors Retinoic acid actions through mammalian nuclear receptors.Imaging myocardial metabolic remodeling.Upregulation of PPARbeta/delta is associated with structural and functional changes in the type I diabetes rat diaphragm Lipotoxicity in the heart.Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators Traditional Chinese Medication Qiliqiangxin Protects Against Cardiac Remodeling and Dysfunction in Spontaneously Hypertensive Rats.PPARbeta activation inhibits melanoma cell proliferation involving repression of the Wilms' tumour suppressor WT1.Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma The peroxisome proliferator-activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy.Radionuclide imaging of myocardial metabolism Translation of myocardial metabolic imaging concepts into the clinics.PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.Genome wide response to dietary tetradecylthioacetic acid supplementation in the heart of Atlantic Salmon (Salmo salar L).Conditional PPARγ knockout from cardiomyocytes of adult mice impairs myocardial fatty acid utilization and cardiac function.MEK1 inhibits cardiac PPARα activity by direct interaction and prevents its nuclear localization.Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart The molecular and metabolic influence of long term agmatine consumption Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.Synthesis and evaluation of 15-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)pentadecanoic acid: a potential PET tracer for studying myocardial fatty acid metabolism.Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection.Glycogen content regulates peroxisome proliferator activated receptor-∂ (PPAR-∂) activity in rat skeletal muscle Targeting metabolic disturbance in the diabetic heart.Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function.Cardiomyocyte-Restricted Deletion of PPARβ/δ in PPARα-Null Mice Causes Impaired Mitochondrial Biogenesis and Defense, but No Further Depression of Myocardial Fatty Acid Oxidation Muscle as a "mediator" of systemic metabolism Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function.Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2 Maintaining ancient organelles: mitochondrial biogenesis and maturation.

P2860

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P2860

Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.

http://www.wikidata.org/entity/Q36151679

description

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Nuclear receptors PPARbeta/del ...... y programs in the mouse heart.

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Nuclear receptors PPARbeta/del ...... y programs in the mouse heart.

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Nuclear receptors PPARbeta/del ...... y programs in the mouse heart.

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Nuclear receptors PPARbeta/del ...... y programs in the mouse heart.

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P2093

Carolyn M Gierasch

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Daniel P Kelly

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Eileen M Burkart

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Kooresh Shoghi

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Michael Courtois

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Michael J Welch

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Nandakumar Sambandam

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Richard W Gross

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Xianlin Han

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P2860

PPARdelta regulates glucose metabolism and insulin sensitivity

PPAR delta: a dagger in the heart of the metabolic syndrome.

Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

Peroxisome proliferator-activated receptors: nuclear control of metabolism

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism

Global and societal implications of the diabetes epidemic

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine.

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10.1172/JCI32578

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12

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117

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2082147

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