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The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Stimulation of Adenosine A2B Receptor Inhibits Endothelin-1-Induced Cardiac Fibroblast Proliferation and α-Smooth Muscle Actin Synthesis Through the cAMP/Epac/PI3K/Akt-Signaling PathwayIsoform-specific antagonists of exchange proteins directly activated by cAMPEpac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.β2-adrenoceptor activation modulates skin wound healing processes to reduce scarringCyclic nucleotide signalling in kidney fibrosis.Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma.The miR-200 family and its targets regulate type II cell differentiation in human fetal lung.Low-power laser irradiation inhibits arecoline-induced fibrosis: an in vitro studyLow-glucose enhances keratocyte-characteristic phenotype from corneal stromal cells in serum-free conditionsDefining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblasts.Regulatory T Cells Contribute to the Inhibition of Radiation-Induced Acute Lung Inflammation via Bee Venom Phospholipase A₂ in Mice.Role of hypoxia-inducible factor 1, α subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblastsIncrease in cellular cyclic AMP concentrations reverses the profibrogenic phenotype of cardiac myofibroblasts: a novel therapeutic approach for cardiac fibrosis.Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balanceAdenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis.Ca2+ and cAMP cross-talk in mitochondria.Epac proteins: specific ligands and role in cardiac remodelling.EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.Cell death sensitization of leukemia cells by opioid receptor activationForskolin, a hedgehog signalling inhibitor, attenuates carbon tetrachloride-induced liver fibrosis in rats.Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells.Pharmacological and Activated Fibroblast Targeting of Gβγ-GRK2 After Myocardial Ischemia Attenuates Heart Failure Progression.Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z.Epac is required for exogenous and endogenous stimulation of adenosine A2B receptor for inhibition of angiotensin II-induced collagen synthesis and myofibroblast differentiation.The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.Adenosine A2a Receptor Blockade Diminishes Wnt/β-Catenin Signaling in a Murine Model of Bleomycin-Induced Dermal Fibrosis.Roles of PDE1 in Pathological Cardiac Remodeling and Dysfunction.How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
cAMP and Epac in the regulation of tissue fibrosis.
@ast
cAMP and Epac in the regulation of tissue fibrosis.
@en
type
label
cAMP and Epac in the regulation of tissue fibrosis.
@ast
cAMP and Epac in the regulation of tissue fibrosis.
@en
prefLabel
cAMP and Epac in the regulation of tissue fibrosis.
@ast
cAMP and Epac in the regulation of tissue fibrosis.
@en
P2093
P2860
P1476
cAMP and Epac in the regulation of tissue fibrosis
@en
P2093
Aaron Snead
Hongruo Yun
Loren Brown
Nakon Aroonsakool
Paul A Insel
Silvia Romano
Utako Yokoyama
P2860
P304
P356
10.1111/J.1476-5381.2012.01847.X
P407
P50
P577
2012-05-01T00:00:00Z