Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
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Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors.Progressive Enrichment of Stemness Features and Tumor Stromal Alterations in Multistep Hepatocarcinogenesis.Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice.Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway.Cancer Stem cells and their cellular origins in primary liver and biliary tract cancers.Liver regeneration - mechanisms and models to clinical application.Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.Animal models of biliary injury and altered bile acid metabolism.Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population.Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice.Hepatocyte selection medium-enriched hepatocellular carcinoma cells are positive for α-fetoprotein and CD44.Liver Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice.Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesisFOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice.Liver inflammation and cancer: The role of tissue microenvironment in generating the tumor-promoting niche (TPN) in the development of hepatocellular carcinoma.Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.Fate tracing of hepatocytes in mouse liver.Road to stemness in hepatocellular carcinoma.The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice without Affecting Regeneration.Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.The Role of Cancer-Associated Fibroblasts and Fibrosis in Liver Cancer.Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers.Differentiation-inducing therapeutic effect of Notch inhibition in reversing malignant transformation of liver normal stem cells via MET.CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance
P2860
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P2860
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Hepatocellular carcinoma origi ...... rogenitor/biliary compartment.
@ast
Hepatocellular carcinoma origi ...... rogenitor/biliary compartment.
@en
type
label
Hepatocellular carcinoma origi ...... rogenitor/biliary compartment.
@ast
Hepatocellular carcinoma origi ...... rogenitor/biliary compartment.
@en
prefLabel
Hepatocellular carcinoma origi ...... rogenitor/biliary compartment.
@ast
Hepatocellular carcinoma origi ...... rogenitor/biliary compartment.
@en
P2093
P2860
P50
P356
P1476
Hepatocellular carcinoma origi ...... progenitor/biliary compartment
@en
P2093
Achim Weber
Arlind Adili
Detian Yuan
Frédéric P Lemaigre
Ingmar Mederacke
Isabelle A Leclercq
Mathias Heikenwälder
Regina Español-Suñer
Robert F Schwabe
Silvia Affò
P2860
P304
P356
10.1172/JCI77995
P407
P577
2015-09-08T00:00:00Z