Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo. - Wikidata - wikimedia - TriplyDB

Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.

Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.

http://www.wikidata.org/entity/Q36168205

about

The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome Role of the inflammasome, IL-1β, and IL-18 in bacterial infections Duality of lipid mediators in host response against Mycobacterium tuberculosis: good cop, bad cop Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship Immune vulnerability of infants to tuberculosis Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections Interaction of Mycobacterium tuberculosis with host cell death pathways Versatile myeloid cell subsets contribute to tuberculosis-associated inflammation Prion pathogenesis in the absence of NLRP3/ASC inflammasomes BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming Contribution of metabolic reprogramming to macrophage plasticity and function Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins NLRP3 inflammasome activation induced by engineered nanomaterials Tuberculosis vaccines: barriers and prospects on the quest for a transformative tool Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice Tim3 binding to galectin-9 stimulates antimicrobial immunity Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection Activation and regulation of the inflammasomes The inflammasome NLRs in immunity, inflammation, and associated diseases Sterile inflammation: sensing and reacting to damage TLR signaling is required for Salmonella typhimurium virulence Profiling early lung immune responses in the mouse model of tuberculosis.Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1.Primary transcriptomes of Mycobacterium avium subsp. paratuberculosis reveal proprietary pathways in tissue and macrophages.CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection.Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity.In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice.Type I IFN induces IL-10 production in an IL-27-independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium tuberculosis-infected macrophages.Altered CD8(+) T cell frequency and function in tuberculous lymphadenitis.Cell-autonomous effector mechanisms against mycobacterium tuberculosis.Distinct contributions of interleukin-1α (IL-1α) and IL-1β to innate immune recognition of Pseudomonas aeruginosa in the lung.Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis.Autophagy in tuberculosis

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P2860

Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.

http://www.wikidata.org/entity/Q36168205

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

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Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

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type

label

Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

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Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

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Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

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Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

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JIMMUNOL.0904189

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Journal of Immunology

P1476

Caspase-1 independent IL-1beta ...... require TLR signaling in vivo.

@en

P2093

Alan Sher

http://www.w3.org/2001/XMLSchema#string

Allen Cheever

http://www.w3.org/2001/XMLSchema#string

Daniel L Barber

http://www.w3.org/2001/XMLSchema#string

David Kugler

http://www.w3.org/2001/XMLSchema#string

Dirk Schlueter

http://www.w3.org/2001/XMLSchema#string

Fayyaz S Sutterwala

http://www.w3.org/2001/XMLSchema#string

Gabriel Núñez

http://www.w3.org/2001/XMLSchema#string

Katrin D Mayer-Barber

http://www.w3.org/2001/XMLSchema#string

Kevin Shenderov

http://www.w3.org/2001/XMLSchema#string

Mark S Wilson

http://www.w3.org/2001/XMLSchema#string

P2860

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

How dying cells alert the immune system to danger

Immunological and inflammatory functions of the interleukin-1 family

Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock.

Immunity to tuberculosis.

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis.

P304

3326-3330

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scholarly article

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10.4049/JIMMUNOL.0904189

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P407

P433

7

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P478

184

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2010-03-03T00:00:00Z

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P5875

41722084

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P698

20200276

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P921

Mycobacterium tuberculosis

Toll-like receptor

P932

3420351

http://www.w3.org/2001/XMLSchema#string