Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels
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Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castleLive cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivoCXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunityGene deletion of P-Selectin and ICAM-1 does not inhibit neutrophil infiltration into peritoneal cavity following cecal ligation-punctureInvolvement of beta-chemokines in the development of inflammatory demyelinationPhosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and CognitionLeukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory diseaseRedox control of microglial function: molecular mechanisms and functional significanceNeuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrierTemporal pattern of ICAM-I mediated regulatory T cell recruitment to sites of inflammation in adoptive transfer model of multiple sclerosis.Vascular, glial, and lymphatic immune gateways of the central nervous systemThe blood-brain-barrier in multiple sclerosis: functional roles and therapeutic targetingT cell-antigen-presenting cell interactions visualized in vivo in a model of antigen-specific inflammation.Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunityIntravital microscopy identifies selectins that regulate T cell traffic into allografts.Comparison of immortalized bEnd5 and primary mouse brain microvascular endothelial cells as in vitro blood-brain barrier models for the study of T cell extravasation.Alpha4beta1 integrin mediates the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis.Gene and protein expression profiling of the microvascular compartment in experimental autoimmune encephalomyelitis in C57Bl/6 and SJL mice.Immune complexes alter cerebral microvessel permeability: roles of complement and leukocyte adhesion.LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.Hello from the Other Side: How Autoantibodies Circumvent the Blood-Brain Barrier in Autoimmune Encephalitis.Knocking at the brain's door: intravital two-photon imaging of autoreactive T cell interactions with CNS structuresDeveloping therapeutics for the treatment of multiple sclerosisLymphocyte homing to bronchus-associated lymphoid tissue (BALT) is mediated by L-selectin/PNAd, alpha4beta1 integrin/VCAM-1, and LFA-1 adhesion pathwaysA new dynamic in vitro modular capillaries-venules modular system: cerebrovascular physiology in a box.Leukocyte extravasation: an immunoregulatory role for alpha-L-fucosidase?P-selectin contributes to severe experimental malaria but is not required for leukocyte adhesion to brain microvasculatureHuman cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.CD44 and HCELL: preventing hematogenous metastasis at step 1.Immunomodulation of experimental allergic encephalomyelitis by cinnamon metabolite sodium benzoate.Mechanisms of disease: the blood-brain barrier.Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAEMechanisms of dendritic cell trafficking across the blood-brain barrier.Overlapping roles of endothelial selectins and vascular cell adhesion molecule-1 in immune complex-induced leukocyte recruitment in the cremasteric microvasculature.Rho GTPases and leucocyte-induced endothelial remodelling.Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitisMolecular and cellular mechanisms of pulmonary fibrosis.Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis.Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell-Mediated Central Nervous System Autoimmune Disease.Pharmacological properties, toxicology and scientific rationale for the use of natalizumab (Tysabri) in inflammatory diseases.
P2860
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P2860
Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@ast
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@en
type
label
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@ast
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@en
prefLabel
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@ast
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@en
P2093
P2860
P356
P1476
Alpha4-integrin-VCAM-1 binding ...... CNS white matter microvessels
@en
P2093
Engelhardt B
Laschinger M
Vajkoczy P
P2860
P304
P356
10.1172/JCI12440
P407
P577
2001-08-01T00:00:00Z