Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning. - Wikidata - wikimedia - TriplyDB

Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning.

Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning.

http://www.wikidata.org/entity/Q36174266

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Zyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of action Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system Dynorphin, stress, and depression Kappa-opioid ligands in the study and treatment of mood disorders Social defeat stress-induced behavioral responses are mediated by the endogenous kappa opioid system Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse Stress in adolescence and drugs of abuse in rodent models: role of dopamine, CRF, and HPA axis Role of kappa-opioid receptors in stress and anxiety-related behavior.Drug withdrawal conceptualized as a stressor.Stress and VTA synapses: implications for addiction and depression Emotional valence and context of social influences on drug abuse-related behavior in animal models of social stress and prosocial interaction Endogenous opiates and behavior: 2006 Affective cue-induced escalation of alcohol self-administration and increased 22-kHz ultrasonic vocalizations during alcohol withdrawal: role of kappa-opioid receptors.Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the κ-opioid receptor antagonist JDTic.Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence The locus coeruleus: A key nucleus where stress and opioids intersect to mediate vulnerability to opiate abuse.Molecular and genetic substrates linking stress and addiction The effects of kappa-opioid receptor ligands on prepulse inhibition and CRF-induced prepulse inhibition deficits in the rat.Genetic and early environmental contributions to alcohol's aversive and physiological effects.Presynaptic inhibition of diverse afferents to the locus ceruleus by kappa-opiate receptors: a novel mechanism for regulating the central norepinephrine system Loss of environmental enrichment increases vulnerability to cocaine addiction.The development and maintenance of drug addiction Peptide kappa opioid receptor ligands: potential for drug development.Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library Antidepressant-like effects of kappa-opioid receptor antagonists in Wistar Kyoto rats.The role of kappa opioid receptors in stress-induced reinstatement of alcohol seeking in rats Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms Role of the kappa-opioid receptor system in stress-induced reinstatement of nicotine seeking in rats.Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse Stress, sex, and addiction: potential roles of corticotropin-releasing factor, oxytocin, and arginine-vasopressin.Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms The role of kappa-opioid receptor activation in mediating antinociception and addiction.Sex differences in kappa opioid pharmacology Opioid hedonic hotspot in nucleus accumbens shell: mu, delta, and kappa maps for enhancement of sweetness "liking" and "wanting".Effects of buprenorphine on behavioral tests for antidepressant and anxiolytic drugs in mice Kappa opioid receptor activation potentiates the cocaine-induced increase in evoked dopamine release recorded in vivo in the mouse nucleus accumbens.The Nociceptin Receptor as an Emerging Molecular Target for Cocaine Addiction

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P2860

Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning.

http://www.wikidata.org/entity/Q36174266

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2006 nî lūn-bûn

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Prior activation of kappa opio ...... place preference conditioning.

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Prior activation of kappa opio ...... place preference conditioning.

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Neuropsychopharmacology

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Prior activation of kappa opio ...... place preference conditioning.

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Benjamin B Land

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Charles Chavkin

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Jay P McLaughlin

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John E Pintar

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Shuang Li

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P2860

Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance

Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses

U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats

Depression: a new animal model sensitive to antidepressant treatments

Psychotomimesis mediated by kappa opiate receptors

Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens

Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats.

When reverse genetics meets physiology: the use of site-specific recombinases in mice.

G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal.

Neuroadaptive mechanisms of addiction: studies on the extended amygdala.

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