Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
about
Spectrin-based skeleton as an actor in cell signalingReal-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulationRegional and temporal profiles of calpain and caspase-3 activities in postnatal rat brain following repeated propofol administrationPurkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 modelDisruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.Methamphetamine- and trauma-induced brain injuries: comparative cellular and molecular neurobiological substratesAxonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.Knockdown of mu-calpain in Fanconi anemia, FA-A, cells by siRNA restores alphaII spectrin levels and corrects chromosomal instability and defective DNA interstrand cross-link repair.Sialoglycosylation of RBC in visceral leishmaniasis leads to enhanced oxidative stress, calpain-induced fragmentation of spectrin and hemolysis.Involvement of calpain/p35-p25/Cdk5/NMDAR signaling pathway in glutamate-induced neurotoxicity in cultured rat retinal neuronsMembrane cholesterol modulates {beta}-amyloid-dependent tau cleavage by inducing changes in the membrane content and localization of N-methyl-D-aspartic acid receptorsParaneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis.Calpain activation by Wingless-type murine mammary tumor virus integration site family, member 5A (Wnt5a) promotes axonal growth.Moderately elevated intracranial pressure after diffuse traumatic brain injury is associated with exacerbated neuronal pathology and behavioral morbidity in the rat.MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons.Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient miceExclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathiesAcute-phase protein α1-antitrypsin inhibits neutrophil calpain I and induces random migration.Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2)Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner.Collapsin response mediator protein-2 is a calmodulin-binding proteinProteolysis of submembrane cytoskeletal proteins ankyrin-G and αII-spectrin following diffuse brain injury: a role in white matter vulnerability at Nodes of Ranvier.β-Amyloid carrying the Dutch mutation has diverse effects on calpain-mediated toxicity in hippocampal neurons.Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons.Proximal giant neurofilamentous axonopathy in mice genetically engineered to resist calpain and caspase cleavage of α-II spectrin.Hypoxia Activates Calpains in the Nerve Fiber Layer of Monkey Retinal Explants.Axons break in animals lacking beta-spectrin.Membrane Repair: Mechanisms and Pathophysiology.Necrosis- and apoptosis-related Met cleavages have divergent functional consequences8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repairMolecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury.Non-conventional apoptotic response to ionising radiation mediated by N-methyl D-aspartate receptors in immature neuronal cells.Spectrin Breakdown Products (SBDPs) as Potential Biomarkers for Neurodegenerative DiseasesNon-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damageA novel recombinant 6Aβ15-THc-C chimeric vaccine (rCV02) mitigates Alzheimer's disease-like pathology, cognitive decline and synaptic loss in aged 3 × Tg-AD mice.Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization.Mechanistic role of calpains in postischemic neurodegeneration.Reduced early hypoxic/ischemic brain damage is associated with increased GLT-1 levels in mice expressing mutant (P301L) human tau.
P2860
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P2860
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
@ast
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
@en
type
label
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
@ast
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
@en
prefLabel
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
@ast
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.
@en
P1476
Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells
@en
P2093
Czogalla A
Sikorski AF
P2888
P304
P356
10.1007/S00018-005-5097-0
P577
2005-09-01T00:00:00Z