AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells. - Wikidata - wikimedia - TriplyDB

AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells.

AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells.

http://www.wikidata.org/entity/Q36207311

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Genealogy of an ancient protein family: the Sirtuins, a family of disordered members Nutraceuticals in Parkinson's Disease AMPK as a potential anticancer target - friend or foe?Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies Hepatocellular carcinoma: Where there is unmet need Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1 Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.The diverse roles of adiponectin in non-small-cell lung cancer: current data and future perspectives.Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation 20S-Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1-AMP-activated protein kinase activation.Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence.Phyllostachys edulis extract induces apoptosis signaling in osteosarcoma cells, associated with AMPK activation Drugs acting on homeostasis: challenging cancer cell adaptation.Identification of the genes chemosensitizing hepatocellular carcinoma cells to interferon-α/5-fluorouracil and their clinical significance LKB1 and AMPK and the cancer-metabolism link - ten years after A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue.Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?Prognostic significance of AMPK in human malignancies: A meta-analysis.Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1 AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.Expression and clinical significance of Sirt1 in colorectal cancer.Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model.Molecular pathways: adiponectin and leptin signaling in cancer.Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide.LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription.Synergic chemoprevention with dietary carbohydrate restriction and supplementation of AMPK-activating phytochemicals: the role of SIRT1 Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma SIRT1: Regulator of p53 Deacetylation Sirtuin deacetylases as therapeutic targets in the nervous system Metabolic regulation by p53 family members.SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC-1α-mediated mitochondrial biogenesis.Targeting myeloid-derived suppressor cells using a novel adenosine monophosphate-activated protein kinase (AMPK) activator.AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms.SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism.AMPKα1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2.CD74: a new prognostic factor for patients with malignant pleural mesothelioma.Effects of cordycepin on HepG2 and EA.hy926 cells: Potential antiproliferative, antimetastatic and anti-angiogenic effects on hepatocellular carcinoma.AMPK: a contextual oncogene or tumor suppressor?

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P2860

AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells.

http://www.wikidata.org/entity/Q36207311

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

AMPK promotes p53 acetylation ...... f SIRT1 in liver cancer cells.

@ast

AMPK promotes p53 acetylation ...... f SIRT1 in liver cancer cells.

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type

label

AMPK promotes p53 acetylation ...... f SIRT1 in liver cancer cells.

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AMPK promotes p53 acetylation ...... f SIRT1 in liver cancer cells.

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prefLabel

AMPK promotes p53 acetylation ...... f SIRT1 in liver cancer cells.

@ast

AMPK promotes p53 acetylation ...... f SIRT1 in liver cancer cells.

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0008-5472.CAN-12-0429

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Cancer Research

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AMPK promotes p53 acetylation ...... of SIRT1 in liver cancer cells

@en

P2093

Chi-Wai Lee

http://www.w3.org/2001/XMLSchema#string

Edith Yuk-Ting Tse

http://www.w3.org/2001/XMLSchema#string

Heong-Fai Liu

http://www.w3.org/2001/XMLSchema#string

Joyce Man-Fong Lee

http://www.w3.org/2001/XMLSchema#string

Leo Lap-Yan Wong

http://www.w3.org/2001/XMLSchema#string

Veronica Yee-Law Leong

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Yick-Pang Ching

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Histone deacetylases specifically down-regulate p53-dependent gene activation

Negative control of p53 by Sir2alpha promotes cell survival under stress

JNK1 phosphorylates SIRT1 and promotes its enzymatic activity

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

AMPK phosphorylation of raptor mediates a metabolic checkpoint

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

Crystal structure of a SIR2 homolog-NAD complex

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4394-4404

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10.1158/0008-5472.CAN-12-0429

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17

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72

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David Grahame Hardie

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2012-06-22T00:00:00Z

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22728651

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phosphorylation

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3433393

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