Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development
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B-Cell Depletion Promotes Aortic Infiltration of Immunosuppressive Cells and Is Protective of Experimental Aortic Aneurysm.Kynurenine Pathway Activation in Human African TrypanosomiasisBioM2MetDisease: a manually curated database for associations between microRNAs, metabolites, small molecules and metabolic diseases.Crosstalk between Tryptophan Metabolism and Cardiovascular Disease, Mechanisms, and Therapeutic ImplicationsThe Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia.Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases.Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice.Tryptophan depletion under conditions that imitate insulin resistance enhances fatty acid oxidation and induces endothelial dysfunction through reactive oxygen species-dependent and independent pathways.Tryptophan-Derived 3-Hydroxyanthranilic Acid Contributes to Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice In Vivo.Indoleamine 2,3-Dioxygenase (IDO) Enzyme Links Innate Immunity and Altered T-Cell Differentiation in Non-ST Segment Elevation Acute Coronary Syndrome.Plasma microbiome-modulated indole- and phenyl-derived metabolites associate with advanced atherosclerosis and postoperative outcomes.Plasma tryptophan-kynurenine metabolites are altered in HIV infection and associated with progression of carotid artery atherosclerosis.Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet.Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice.An Expanded Neuroimmunomodulation Axis: sCD83-Indoleamine 2,3-Dioxygenase—Kynurenine Pathway and Updates of Kynurenine Pathway in Neurologic Diseases.Indoleamine 2,3-dioxygenase 1 in coronary atherosclerotic plaque enhances tissue factor expression in activated macrophagesC-Type Natriuretic Peptide (CNP) Inhibition of Interferon-γ-Mediated Gene Expression in Human Endothelial Cells In Vitro
P2860
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P2860
Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@ast
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@en
type
label
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@ast
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@en
prefLabel
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@ast
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@en
P2093
P2860
P50
P356
P1476
Indoleamine 2,3-dioxygenase-1 ...... rtunities for drug development
@en
P2093
Alun H Davies
Inhye Park
Marc Feldmann
Michael E Goddard
Nagore Astola
Patricia Green
Richard O Williams
P2860
P304
13033-13038
P356
10.1073/PNAS.1517820112
P407
P577
2015-10-05T00:00:00Z