A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
about
Pharmacokinetic properties of IgG and various Fc fusion proteins in mice.Half-life extended biotherapeutics.Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms.Pharmacokinetic de-risking tools for selection of monoclonal antibody lead candidates.A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life.Evaluation of an FcRn affinity chromatographic method for IgG1-type antibodies and evaluation of IgG variants.
P2860
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
@ast
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
@en
type
label
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
@ast
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
@en
prefLabel
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
@ast
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
@en
P2093
P2860
P1476
A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life
@en
P2093
Colby A Souders
Mark S Klempner
Stuart C Nelson
William Thomas
P2860
P304
P356
10.1080/19420862.2015.1054585
P577
2015-01-01T00:00:00Z