CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells. - Wikidata - wikimedia - TriplyDB

CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.

CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.

http://www.wikidata.org/entity/Q36213722

about

Integration of Signaling Pathways with the Epigenetic Machinery in the Maintenance of Stem Cells ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling Overexpression of DOC-1R inhibits cell cycle G1/S transition by repressing CDK2 expression and activation Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cells Mapping of six somatic linker histone H1 variants in human breast cancer cells uncovers specific features of H1.2.A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesis Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells.LRP in Endothelial Cells: A Little Goes a Long Way.Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK Linking DNA Damage and Hormone Signaling Pathways in Cancer.ARTD1 regulates cyclin E expression and consequently cell-cycle re-entry and G1/S progression in T24 bladder carcinoma cells.Phosphorylation: a fundamental regulator of steroid receptor action.Beyond DNA Repair: Additional Functions of PARP-1 in Cancer.Macro domains as metabolite sensors on chromatin.More help than hindrance: nucleosomes aid transcriptional regulation.Transcriptional roles of PARP1 in cancer.TADs as modular and dynamic units for gene regulation by hormones.Role of PARP-1 in prostate cancer.A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes.BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management.Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer: Current Developments, Therapeutic Strategies, and Future Opportunities.ATM induces MacroD2 nuclear export upon DNA damage Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters.Insight into the machinery that oils chromatin dynamics.Post-translational modifications of the intrinsically disordered terminal domains of histone H1: effects on secondary structure and chromatin dynamics.Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation.Dynamics and dispensability of variant-specific histone H1 Lys-26/Ser-27 and Thr-165 post-translational modifications.Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genes Activation of mitogen- and stress-activated kinase 1 is required for proliferation of breast cancer cells in response to estrogens or progestins.DNA damage and gene transcription: accident or necessity?Identifying Direct Protein Targets of Poly-ADP-Ribose Polymerases (PARPs) Using Engineered PARP Variants-Orthogonal Nicotinamide Adenine Dinucleotide (NAD+) Analog Pairs.Novel insights into the neuroendocrine control of inflammation: the role of GR and PARP1.PARty promoters: hormone-dependent gene regulation requires CDK2 activation of PARP1.Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome.The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis.Barcelona conference on epigenetics and cancer 2016 - beyond cancer genomes.Signaling by Steroid Hormones in the 3D Nuclear Space.Role of novel histone modifications in cancer.PARP1 promoter links cell cycle progression with adaptation to oxidative environment.

P2860

Q26769986-656F9D0B-11D2-4311-AE43-148EA01533E6 Q28114985-DCC8F3BB-D0DC-44F7-8B85-11C5E97621CF Q28941776-C719F106-C5DE-45F2-9FFB-D0D89CEB383E Q34362853-6A747FEA-4DA9-48B5-8B91-AB6C61018A0F Q34400888-7CADC690-5767-4163-A822-1E1B4CDADF9F Q34435100-A424C113-CB27-469F-83C3-A39415AC2A8F Q35113788-F449A5F5-8060-4241-B8A8-F7693356B85F Q36519473-BD4E93C3-315F-4020-AD05-726E0117D843 Q36688106-E1A7FBD8-0806-46A4-A870-896F003E353A Q36730819-B6882FFD-E0CC-4C99-A19D-9D95B6754475 Q37143195-94C2415F-C9C7-47BB-A5B5-AB4CC0340CA1 Q37198642-394FA17B-835E-4344-B588-BDD12EB6F9A1 Q37346306-36D659BC-507F-48BF-AF11-FCC5F7B421D5 Q38086003-C79C488C-1176-4705-98F7-6C79513E58FC Q38113645-C7E2DAD4-4853-452F-92DB-11DB1F6B81F7 Q38219235-E0D2C2D2-AF6F-4A3F-A935-15F7BDA97CAC Q38503197-32FFDA2C-603F-490C-AA35-A792E2E99BF8 Q38526322-CE637A5D-4695-4286-8B26-D7F4C15C2724 Q38636544-4EBD5679-1811-4B43-9164-4E2A915A9247 Q38669183-E0A70AF6-B9A9-4C51-A212-A8561E3C1DFA Q38683171-504E7CB8-756C-44BF-848C-E7AC564014F3 Q38722174-33F2CA06-F127-4378-93DA-8B20DAF9F270 Q38759210-33B3087C-DC68-4F16-A5A1-8ACC103A825E Q38789935-31F16B69-F55B-4893-942D-31A9594A7B10 Q38813372-77A4C503-609F-432E-9CDB-C102987BEC8D Q38951482-B5BDB3A8-96AC-4181-B2BF-79792591FE14 Q38990534-8D767A90-F363-41BE-A1EF-B1DCB0F3D3A4 Q39148484-ACD46507-9A95-43D0-ADD7-0987B4580BE3 Q39162952-5038A2A3-AE57-492B-8ED7-DFACD88B3D5C Q41340286-97D1FDC0-6F3E-43C7-8E30-7E4FD6EFD511 Q41910306-469416D4-1BC1-47F6-AF70-EA7DF712D692 Q42781123-33DE347B-05A1-41FC-BEBD-AAF7CEBA58C0 Q42939887-CB2D248E-353C-4876-B7E6-6519F727F9E1 Q44542715-BC8F6755-E0B1-48F0-BFEF-AA8FB0CCB9B1 Q47136688-5ED42AA2-563B-49C7-88B5-31BD23F908D5 Q47577915-FEE5F5F4-84B6-4FD6-8160-04ACB432E9A7 Q48184878-59928DDD-05A1-4C2B-904A-26E1F7488653 Q52655031-5785CED4-7231-4F88-8255-D0BFCB2885A1 Q55312472-1B8AFEE1-28DF-404B-BCAA-A7001D47E4CA

P2860

CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.

http://www.wikidata.org/entity/Q36213722

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

CDK2-dependent activation of P ...... lation in breast cancer cells.

@ast

CDK2-dependent activation of P ...... lation in breast cancer cells.

@en

type

label

CDK2-dependent activation of P ...... lation in breast cancer cells.

@ast

CDK2-dependent activation of P ...... lation in breast cancer cells.

@en

prefLabel

CDK2-dependent activation of P ...... lation in breast cancer cells.

@ast

CDK2-dependent activation of P ...... lation in breast cancer cells.

@en

P1433

Q36213722-9F9B870C-20EF-499E-9D78-0922ADB99710

P1476

Q36213722-E99673BF-019B-42B9-9F4F-9383BDD41530

P2093

Q36213722-636BA478-5207-4335-A0AF-5342BC54074F

Q36213722-E56B34D7-DD65-4B79-B5FF-7A6673D05DAE

Q36213722-FE79D87E-4559-42C5-9416-1BC41C744B07

Q36213722-FF9BE96E-8A9B-408D-95B5-EC61F8E19D0F

P2860

Q36213722-02BE6704-8658-4A4A-98CF-E33503646865

Q36213722-04061DC7-2EF0-499D-9FA8-67ED0CFDAED0

Q36213722-0EECA0D5-2350-4D76-A4BE-5A8C139D9E1A

Q36213722-2425BADB-92CB-45D5-8979-0B1A6807FB81

Q36213722-2D8A4513-2BD2-4E8D-BD9C-B90AE714324D

Q36213722-4201B231-AD98-46FC-B67F-9E8101C61E6E

Q36213722-50DDF615-15A2-48B6-93A1-E881A1735C8D

Q36213722-516F90DC-0C8E-42BF-8EF0-6A521CD88239

Q36213722-54889749-13DF-4F40-936B-C901CA47E1EB

Q36213722-572E13B4-E404-430D-90E5-159EB39B7036

P304

Q36213722-5DF7BFC4-AC35-4C3C-9DFC-AA890E36F06A

P31

Q36213722-7B53EE17-07CC-4004-B0F8-B484EF8D27FD

P356

Q36213722-F04EF6EC-9FBE-4C5E-A6C0-E698261B78E1

P433

Q36213722-3955E0E5-F5A6-47F1-A828-D47457A8327F

P478

Q36213722-36505D84-19C7-4725-B099-69C2227D02E7

P50

Q36213722-45BA5CD9-B1D7-456B-BE9C-8480395EF8F2

Q36213722-8836C83A-1ABB-4C77-91E3-A6BAB594B62B

Q36213722-916AEA2B-121D-4EAC-B0A1-37AA3A8DC690

Q36213722-F8685862-3F5B-41F2-B2A1-ED5ACF85E8BA

Q36213722-FA18F70A-C7F2-41F1-9CDF-6124C80E70E1

Q36213722-FABBA2D0-2398-4EA3-87F0-2DFB7D3AF894

P577

Q36213722-EF9A8BFD-0E4A-433E-A614-DD6AFC19C09E

P5875

Q36213722-2D0B86E8-8D66-4B41-8772-1E4AD29324E2

P698

Q36213722-6D0768AC-356C-45BD-9BA9-EBBE389BB677

P932

Q36213722-08B0D6DA-37D4-465F-89F4-A89B694C59F8

P356

P1433

Genes & Development

P1476

CDK2-dependent activation of P ...... ulation in breast cancer cells

@en

P2093

A Silvina Nacht

http://www.w3.org/2001/XMLSchema#string

Baldo Oliva

http://www.w3.org/2001/XMLSchema#string

Daniel Soronellas

http://www.w3.org/2001/XMLSchema#string

Francois Le Dily

http://www.w3.org/2001/XMLSchema#string

P2860

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway

Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator.

A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors

Nicotinamide mononucleotide activation of new DNA-dependent polyadenylic acid synthesizing nuclear enzyme.

The PARP superfamily.

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

P304

1972-1983

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.193193.112

http://www.w3.org/2001/XMLSchema#string

P433

17

http://www.w3.org/2001/XMLSchema#string

P478

26

http://www.w3.org/2001/XMLSchema#string

P50

Cecilia Ballaré

Roni H. G. Wright

Giancarlo Castellano

Jofre Font-Mateu

Miguel Beato del Rosal

P577

2012-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230797586

http://www.w3.org/2001/XMLSchema#string

P698

22948662

http://www.w3.org/2001/XMLSchema#string

P932

3435499

http://www.w3.org/2001/XMLSchema#string