Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. - Wikidata - wikimedia - TriplyDB

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

http://www.wikidata.org/entity/Q34598646

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S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1 PARP-1 transcriptional activity is regulated by sumoylation upon heat shock Associations between polymorphisms in DNA repair genes and glioblastoma Trial watch - inhibiting PARP enzymes for anticancer therapy Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation Base Excision Repair, a Pathway Regulated by Posttranslational Modifications ADP-ribosyltransferases and poly ADP-ribosylation Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition.Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Functional Aspects of PARP1 in DNA Repair and Transcription.PolyADP-ribosylation is required for pronuclear fusion during postfertilization in mice.Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase.Regulation of mitochondrial poly(ADP-Ribose) polymerase activation by the β-adrenoceptor/cAMP/protein kinase A axis during oxidative stress.Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease.Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of peripheral neuropathy in a streptozotocin-induced mouse model of diabetes.Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.Mechanistic insight into DNA damage and repair in ischemic stroke: exploiting the base excision repair pathway as a model of neuroprotection.PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function.CXC chemokine ligand 12 protects pancreatic β-cells from necrosis through Akt kinase-mediated modulation of poly(ADP-ribose) polymerase-1 activity.Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway.The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation New PARP targets for cancer therapy Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins.SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants.Cardiovascular Protective Effect of Metformin and Telmisartan: Reduction of PARP1 Activity via the AMPK-PARP1 Cascade Oxidative stress and NAD+ in ischemic brain injury: current advances and future perspectives.Regulation of chromatin structure by poly(ADP-ribosyl)ation.CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.NF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1 Novel modulators of poly(ADP-ribose) polymerase.Thromboxane A2 Receptor Stimulation Enhances Microglial Interleukin-1β and NO Biosynthesis Mediated by the Activation of ERK Pathway

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P2860

Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.

http://www.wikidata.org/entity/Q34598646

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2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年学术文章

@wuu

2006年学术文章

@zh-cn

2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

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name

Direct phosphorylation and regulation of poly

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Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

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Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

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type

label

Direct phosphorylation and regulation of poly

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Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

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Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

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prefLabel

Direct phosphorylation and regulation of poly

@nl

Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

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Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

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PNAS.0508606103

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Proceedings of the National Academy of Sciences of the United States of America

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Direct phosphorylation and reg ...... signal-regulated kinases 1/2.

@en

P2093

Amanda K Wiggins

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Raymond A Swanson

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Sang Won Suh

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Wai Y Chan

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P2860

The role of poly(ADP-ribose) in the DNA damage signaling network

Long-term memory requires polyADP-ribosylation

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

The activation of MAP kinase and p34cdc2/cyclin B during the meiotic maturation of Xenopus oocytes.

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

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10.1073/PNAS.0508606103

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18

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103

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Tiina M. Kauppinen

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2006-04-20T00:00:00Z

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7152251

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identical protein binding

phosphorylation

Mitogen-activated protein kinase 1

Mitogen-activated protein kinase 3

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1459030

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