Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
about
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures.Targeting protein kinases to reverse multidrug resistance in sarcoma.Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells.Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.TIMP3 regulates osteosarcoma cell migration, invasion, and chemotherapeutic resistances.Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines.Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer CellsInhibitory effects of low-intensity pulsed ultrasound sonication on the proliferation of osteosarcoma cells.The IGF-1R/AKT pathway determines cell fate in response to p53.Tectorigenin inhibits osteosarcoma cell migration through downregulation of matrix metalloproteinases in vitro.MK-2206 co-treatment with 5-fluorouracil or doxorubicin enhances chemosensitivity and apoptosis in gastric cancer by attenuation of Akt phosphorylation.
P2860
Q36315289-CBBA58F6-4A2A-4053-B5A7-8C17199D4949Q36527950-5FC0E77D-1012-4187-9656-283BB74E7CC6Q36640092-00BBF859-D5DC-49B2-92E4-273D09683BC9Q37317313-4169E7D9-BDCE-4807-A711-5974C9C7D7BDQ38805212-26ECFEB5-48A1-4DB8-99E5-EFEF1D6192DAQ41093512-26068257-66C6-484F-84AA-1B90434503A1Q41470356-D40E9398-2422-4FC2-A158-64C6BB0CAB1CQ41611452-12B110E8-25FC-4BB4-B8C1-CBCD3DF962F0Q41687394-CA1AC47C-ADED-4438-A4C2-BC3BC444B35CQ42099762-A0572C65-47EB-4DDF-8F1C-E6FBD589B589Q42128983-0197D1BC-3739-4FCD-8CE0-66E471DEFC76
P2860
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@ast
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@en
type
label
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@ast
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@en
prefLabel
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@ast
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@en
P2093
P2860
P1476
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
@en
P2093
Carl G Maki
Michael Hansen
Ricardo E Perez
Steven Gitelis
P2860
P304
P356
10.4161/15384047.2014.961876
P577
2014-01-01T00:00:00Z