Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
about
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.Identification of glycogen synthase kinase 3α as a therapeutic target in melanomaKnockdown of Aurora-B inhibits osteosarcoma cell invasion and migration via modulating PI3K/Akt/NF-κB signaling pathway.Let-7g reverses malignant phenotype of osteosarcoma cells by targeting Aurora-B.Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers.miRNA-130b is required for the ERK/FOXM1 pathway activation-mediated protective effects of isosorbide dinitrate against mesenchymal stem cell senescence induced by high glucose.Stepwise group sparse regression (SGSR): gene-set-based pharmacogenomic predictive models with stepwise selection of functional priors.Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy.The Novel ATP-Competitive MEK/Aurora Kinase Inhibitor BI-847325 Overcomes Acquired BRAF Inhibitor Resistance through Suppression of Mcl-1 and MEK ExpressionInvestigation of FOXM1 as a Potential New Target for Melanoma.Tubulin Beta3 Serves as a Target of HDAC3 and Mediates Resistance to Microtubule-Targeting Drugs.Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells.FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells.Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors.Mitochondrial oxidative stress is the Achille's heel of melanoma cells resistant to Braf-mutant inhibitor.Inhibition of Aurora-B suppresses osteosarcoma cell migration and invasion.Mechanisms of RAS/β-catenin interactions.Immune consequences of kinase inhibitors in development, undergoing clinical trials and in current use in melanoma treatment.Cell Cycle Regulation and Melanoma.Knockdown of Aurora-B alters osteosarcoma cell malignant phenotype via decreasing phosphorylation of VCP and NF-κB signaling.Expression of Aurora-B and FOXM1 predict poor survival in patients with nasopharyngeal carcinoma.Iciartin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling.RNA interference-mediated knockdown of Aurora-B alters the metastatic behavior of A549 cells via modulation of the phosphoinositide 3-kinase/Akt signaling pathway.Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype.Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin.
P2860
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P2860
Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Aurora B is regulated by the m ...... tial target in melanoma cells.
@ast
Aurora B is regulated by the m ...... tial target in melanoma cells.
@en
type
label
Aurora B is regulated by the m ...... tial target in melanoma cells.
@ast
Aurora B is regulated by the m ...... tial target in melanoma cells.
@en
prefLabel
Aurora B is regulated by the m ...... tial target in melanoma cells.
@ast
Aurora B is regulated by the m ...... tial target in melanoma cells.
@en
P2093
P2860
P356
P1476
Aurora B is regulated by the m ...... tial target in melanoma cells.
@en
P2093
Caroline Bonet
Corine Bertolotto
Karine Bille
Maryline Allegra
Mickaël Ohanna
Philippe Bahadoran
Robert Ballotti
Sandy Giuliano
Stéphane Rocchi
P2860
P304
29887-29898
P356
10.1074/JBC.M112.371682
P407
P577
2012-07-05T00:00:00Z