Cardiac and skeletal muscle disorders caused by mutations in the intracellular Ca2+ release channels.
about
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.The channelopathies: novel insights into molecular and genetic mechanisms of human diseaseCharacterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardiaGenetic testing of inherited arrhythmias.Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.Ryanodine receptor channelopathies.Inositol trisphosphate receptor Ca2+ release channels.Cardiac ryanodine receptor phosphorylation: target sites and functional consequencesIn situ confocal imaging in intact heart reveals stress-induced Ca(2+) release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptor(R4496C+/-) mutationLocalization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor.Malignant hyperthermia: a pharmacogenetic disorder.Chain-reaction Ca(2+) signaling in the heart.Stressed out: the skeletal muscle ryanodine receptor as a target of stressFrom molecule to malady.Altered cardiac myocyte Ca regulation in heart failure.Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes.Ryanodine receptors, calcium signaling, and regulation of vascular tone in the cerebral parenchymal microcirculation.In situ calcium signaling: no calcium sparks detected in rat myometrium.Molecular and electrophysiological bases of catecholaminergic polymorphic ventricular tachycardia.Ryanodine receptor-mediated arrhythmias and sudden cardiac death.A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses.The role of genetic testing in paediatric syndromes of sudden death: state of the art and future considerations.Cardiac Channelopathies and Sudden Death: Recent Clinical and Genetic AdvancesChannelopathies linked to plasma membrane phosphoinositides.Characterization of Ca(2+)-Dependent Protein-Protein Interactions within the Ca(2+) Release Units of Cardiac Sarcoplasmic Reticulum.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia.Modulation of SR Ca2+ release by the triadin-to-calsequestrin ratio in ventricular myocytes.A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease.Diversification of the muscle proteome through alternative splicing.Early administration of nifedipine protects against angiotensin II-induced cardiomyocyte hypertrophy through regulating CaMKII-SERCA2a pathway and apoptosis in rat cardiomyocytes.Brugada Syndrome Unmasked by Accidental Inhalation of Gasoline Vapors
P2860
Q24301857-1640ABEE-6E63-4BBB-AA10-2E833FE75C5FQ24532317-3A5C04B6-F41B-4908-8834-E8DD4ECCBEEAQ33159040-F81C04A7-3141-405A-BE60-F05533424A5FQ33161113-D04AC802-F3FE-4B27-8A0F-B7C41E04F372Q33565617-9376F45A-EE1F-4DB9-9D18-8E1D8D0E3BF4Q33912937-A83489A0-1415-4B42-90B6-FA62C8D1731CQ33983069-F69A6FF7-6B71-4349-98C8-A0014419DA0AQ33995185-BD2687A1-3DD9-45FD-8A1E-5CB620CC0AE3Q34313368-3E83F1DC-8EE6-448A-9B98-88754C867667Q34752142-8B8A61F3-1710-42C8-917A-B415BA303EEDQ34883560-A2A0AE71-D863-4710-824A-5A4A4587D497Q35865391-0B2460CF-C6FB-4670-BBDB-90883A12F2C3Q36407033-71F42E9D-2CC2-49F8-9EA8-C1427F890060Q36428969-60258710-CA4B-4D09-AAE5-5B2F0C8DEA76Q36659965-06D5C85A-14F6-4655-9DA8-81D05AE0BC9CQ36667318-A664B3B2-0E86-478D-A990-C1AE092C5719Q36729418-E97DCBF1-FD49-4814-888F-82B97721CE38Q36736966-07CD1136-902A-4F0C-9200-21AEFE0CA36BQ36853107-EAF512AF-B0C3-48D1-8069-78FCDC57F834Q37248371-41CE0C2C-A092-4B40-9EF5-7D8FC8A275A6Q37305886-183C90A8-8F8B-4D90-B889-1D2BC5C4DB64Q37621582-80197A3F-8EB4-4765-839E-96BDA492FC77Q37728178-B10D2580-5774-4BC6-BCD3-BF60FCFB4A13Q37732004-E2A04727-3683-4787-855A-9C5ADF5091A4Q38541159-BE5AECB2-3C58-4AA3-8ECB-2F418F3E742BQ39038606-46867D1C-E71D-4536-8782-5E93FF11FC59Q39978369-87E78D01-C1BD-4923-A03C-01332808E137Q42503629-1FCEFEBB-E933-4494-8828-30077585ACD6Q43118021-4BB808EF-BB80-436F-A6C7-2B38A32F9EF3Q49577286-6FB9E3EC-BFFD-49F0-9722-2AD6F3B78746Q52671372-B27F7E15-99C6-4758-92BE-790702AA7188Q52881074-B449AA69-F0C9-4BFB-9464-ED7336E16FC8Q57805930-46FDFA53-F7DC-4EAB-9AA4-98928954DC3C
P2860
Cardiac and skeletal muscle disorders caused by mutations in the intracellular Ca2+ release channels.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Cardiac and skeletal muscle di ...... ellular Ca2+ release channels.
@ast
Cardiac and skeletal muscle di ...... ellular Ca2+ release channels.
@en
type
label
Cardiac and skeletal muscle di ...... ellular Ca2+ release channels.
@ast
Cardiac and skeletal muscle di ...... ellular Ca2+ release channels.
@en
prefLabel
Cardiac and skeletal muscle di ...... ellular Ca2+ release channels.
@ast
Cardiac and skeletal muscle di ...... ellular Ca2+ release channels.
@en
P2860
P356
P1476
Cardiac and skeletal muscle di ...... cellular Ca2+ release channels
@en
P2093
Silvia G Priori
P2860
P304
P356
10.1172/JCI25664
P407
P577
2005-08-01T00:00:00Z