Doxycycline hinders phenylalanine fibril assemblies revealing a potential novel therapeutic approach in phenylketonuria

about

Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations.Metabolite amyloids: a new paradigm for inborn error of metabolism disorders.

P2860

Q48172417-45E38AE9-BB2B-4AD5-A845-88A226679A54 Q50238179-3544F656-29B6-4E83-89AD-D005D5534FC2

P2860

Doxycycline hinders phenylalanine fibril assemblies revealing a potential novel therapeutic approach in phenylketonuria

Item

http://www.wikidata.org/entity/Q36221601

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@ast

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@en

type

Item

label

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@ast

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@en

prefLabel

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@ast

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@en

P1476

Doxycycline hinders phenylalan ...... ic approach in phenylketonuria

@en

P2093

Ada De Luigi

http://www.w3.org/2001/XMLSchema#string

Andrea Re Depaolini

http://www.w3.org/2001/XMLSchema#string

Ehud Gazit

http://www.w3.org/2001/XMLSchema#string

Laura Cantù

http://www.w3.org/2001/XMLSchema#string

Laura Colombo

http://www.w3.org/2001/XMLSchema#string

Luca Russo

http://www.w3.org/2001/XMLSchema#string

P2860

Behavioral and neurochemical characterization of new mouse model of hyperphenylalaninemia

The neuropathology of phenylketonuria: human and animal studies.

Anti-amyloidogenic activity of tetracyclines: studies in vitro.

A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis

Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils.

Human phenylalanine hydroxylase gene expression in kidney and other nonhepatic tissues.

Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction.

Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.

Phenylalanine hydroxylase deficiency.

Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria.

P2888

srep15902

P304

15902

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SREP15902

http://www.w3.org/2001/XMLSchema#string

P407

English

P478

http://www.w3.org/2001/XMLSchema#string

P50

Lihi Adler-Abramovich

Massimiliano De Paola

A Mariani

P577

2015-10-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

283974164

http://www.w3.org/2001/XMLSchema#string

P698

26510963

http://www.w3.org/2001/XMLSchema#string

P921

phenylketonuria

P932

4625134

http://www.w3.org/2001/XMLSchema#string

Doxycycline hinders phenylalanine fibril assemblies revealing a potential novel therapeutic approach in phenylketonuria

about

P2860

P2860

Doxycycline hinders phenylalanine fibril assemblies revealing a potential novel therapeutic approach in phenylketonuria

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P478

P50

P577

P5875

P698

P921

P932