Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.
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An atomic model for the pleated beta-sheet structure of abeta amyloid protofilamentsPauling and Corey's alpha-pleated sheet structure may define the prefibrillar amyloidogenic intermediate in amyloid diseaseA helical structural nucleus is the primary elongating unit of insulin amyloid fibrilsA mathematical model of the kinetics of beta-amyloid fibril growth from the denatured stateUltrastructural organization of amyloid fibrils by atomic force microscopy.Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance.A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMRMultiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrilsBinding mode of Thioflavin T and other molecular probes in the context of amyloid fibrils-current statusSpontaneous fibril formation by polyalanines; discontinuous molecular dynamics simulationsOrientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptideProbing protein aggregation using discrete molecular dynamicsCryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing.Structural polymorphism of Alzheimer Abeta and other amyloid fibrilsUltrafast colorimetric determination of predominant protein structure evolution with gold nanoplasmonic particles.Two amyloid States of the prion protein display significantly different folding patternsFiber diffraction data indicate a hollow core for the Alzheimer's aβ 3-fold symmetric fibril.Biophysical studies of the development of amyloid fibrils from a peptide fragment of cold shock protein B.Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells.Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging.Mechanisms of enzymatic degradation of amyloid Beta microfibrils generating nanofilaments and nanospheres related to cytotoxicity.Quantum mechanical studies on model alpha-pleated sheets.X-ray micro-diffraction studies on biological samples at the BioCAT Beamline 18-ID at the Advanced Photon Source.Ultrastructural characterization of peptide-induced membrane fusion and peptide self-assembly in the lipid bilayerMolecular organization of amyloid protofilament-like assembly of betabellin 15D: helical array of beta-sandwiches.A general model for amyloid fibril assembly based on morphological studies using atomic force microscopy.Insertion of Alzheimer's A beta 40 peptide into lipid monolayers.Structure of core domain of fibril-forming PHF/Tau fragments.De novo designed peptide-based amyloid fibrils.A synchrotron-based hydroxyl radical footprinting analysis of amyloid fibrils and prefibrillar intermediates with residue-specific resolution.The role of side-chain interactions in the early steps of aggregation: Molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35.Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease.Zn2+-Aβ40 complexes form metastable quasi-spherical oligomers that are cytotoxic to cultured hippocampal neuronsLight-triggered disassembly of amyloid fibrils.Doxycycline hinders phenylalanine fibril assemblies revealing a potential novel therapeutic approach in phenylketonuriaTurn nucleation perturbs amyloid β self-assembly and cytotoxicity.Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopyDifferences in β-strand populations of monomeric Aβ40 and Aβ42.Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-beta peptide.Surface Induced nanofiber growth by self-assembly of a silk-elastin-like protein polymer.
P2860
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P2860
Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Structural analysis of Alzheimer's beta
@nl
Structural analysis of Alzheim ...... t assembly of tubular fibrils.
@ast
Structural analysis of Alzheim ...... t assembly of tubular fibrils.
@en
type
label
Structural analysis of Alzheimer's beta
@nl
Structural analysis of Alzheim ...... t assembly of tubular fibrils.
@ast
Structural analysis of Alzheim ...... t assembly of tubular fibrils.
@en
prefLabel
Structural analysis of Alzheimer's beta
@nl
Structural analysis of Alzheim ...... t assembly of tubular fibrils.
@ast
Structural analysis of Alzheim ...... t assembly of tubular fibrils.
@en
P2093
P2860
P1433
P1476
Structural analysis of Alzheim ...... nt assembly of tubular fibrils
@en
P2093
Malinchik SB
Szumowski KE
P2860
P304
P356
10.1016/S0006-3495(98)77812-9
P407
P577
1998-01-01T00:00:00Z