Alterations in integrin receptor expression on chemically transformed human cells: specific enhancement of laminin and collagen receptor complexes
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Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagenLaminin-binding integrin alpha 7 beta 1: functional characterization and expression in normal and malignant melanocytesRe-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cellsDiminished expression of integrin adhesion molecules on human colonic epithelial cells during the benign to malign tumour transformation.Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV.Expression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases.Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Correlations with their functions as receptors and cell adhesion molecules.Changes in expression of alpha 6/beta 4 integrin heterodimer in primary and metastatic breast cancer.Integrin expression and ability to adhere to extracellular matrix proteins and endothelial cells in human lung cancer lines.Human lung tumor-associated antigen identified as an extracellular matrix adhesion moleculeN-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells.Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesionBPD-MA-mediated photosensitization in vitro and in vivo: cellular adhesion and beta1 integrin expression in ovarian cancer cellsModulation of in vivo migratory function of alpha 2 beta 1 integrin in mouse liverIntegrin alpha 6 expression in human prostate carcinoma cells is associated with a migratory and invasive phenotype in vitro and in vivoComputerized analysis of tumor cell interactions with extracellular matrix proteins, peptides, and endothelial cells under laminar flow.Expression of VLA-2, VLA-3, and alpha(v) integrin receptors in uveal melanoma: association with microvascular architecture of the tumour and prognostic value.Integrin-type extracellular matrix receptors in cancer and inflammation.Quantification of integrin subunits on human prostatic cell lines--comparison of nontumorigenic and tumorigenic lines.Glioma invasion in the central nervous system.A defect in cell-to-cell adhesion via integrin-fibronectin interactions in a highly metastatic tumor cell line.Characterization of tumorigenic sub-lines from a poorly tumorigenic human colon-adenocarcinoma cell line.Inhibition of cell attachment, invasion and metastasis of human carcinoma cells by anti-integrin beta 1 subunit antibody.Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1The size of the intracellular beta 1-integrin precursor pool regulates maturation of beta 1-integrin subunit and associated alpha-subunits.The tumor microenvironment: possible role of integrins and the extracellular matrix in tumor biological behavior of intratubular germ cell neoplasia and testicular seminomas.VLA-4 molecules on tumor cells initiate an adhesive interaction with VCAM-1 molecules on endothelial cell surface.Characterization of integrin receptors in normal and neoplastic human brain.Alpha 1 beta 1 integrin on neural crest cells recognizes some laminin substrata in a Ca(2+)-independent manner.Differential expression of extracellular matrix molecules and the alpha 6-integrins in the normal and neoplastic prostate.Integrin distributions in renal cell carcinomas of various grades of malignancy.Immunolocalization of alpha 2, alpha 5, and alpha 6 integrin subunits in salivary tissue and adenomas of the parotid gland.Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization.
P2860
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P2860
Alterations in integrin receptor expression on chemically transformed human cells: specific enhancement of laminin and collagen receptor complexes
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Alterations in integrin recept ...... nd collagen receptor complexes
@ast
Alterations in integrin recept ...... nd collagen receptor complexes
@en
type
label
Alterations in integrin recept ...... nd collagen receptor complexes
@ast
Alterations in integrin recept ...... nd collagen receptor complexes
@en
prefLabel
Alterations in integrin recept ...... nd collagen receptor complexes
@ast
Alterations in integrin recept ...... nd collagen receptor complexes
@en
P2860
P356
P1476
Alterations in integrin recept ...... nd collagen receptor complexes
@en
P2093
P2860
P304
P356
10.1083/JCB.110.2.481
P407
P577
1990-02-01T00:00:00Z