Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells.
about
Cellular aspects of prion replication in vitroProteasomes and ubiquitin are involved in the turnover of the wild-type prion proteinCritical significance of the region between Helix 1 and 2 for efficient dominant-negative inhibition by conversion-incompetent prion proteinScrapie-infected mice and PrP knockout mice share abnormal localization and activity of neuronal nitric oxide synthaseLive imaging of prions reveals nascent PrPSc in cell-surface, raft-associated amyloid strings and websCharacterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD.In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies.Cellular biology of prion diseases.Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress.Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylationCholesterol-dependent retention of GPI-anchored proteins in endosomes.Quantitative detection and biological propagation of scrapie seeding activity in vitro facilitate use of prions as model pathogens for disinfectionUltrastructural localization of prion proteins: physiological and pathological implications.Axonal and transynaptic spread of prions.Overexpression of nonconvertible PrPc delta114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation.Scrapie strains maintain biological phenotypes on propagation in a cell line in culture.Differential sorting and fate of endocytosed GPI-anchored proteins.Biological network inferences for a protection mechanism against familial Creutzfeldt-Jakob disease with E200K pathogenic mutation.Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting diseasePrion infection of epithelial Rov cells is a polarized event.Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells.Scrapie prions selectively modify the stress response in neuroblastoma cellsCultured peripheral neuroglial cells are highly permissive to sheep prion infection.A bovine cell line that can be infected by natural sheep scrapie prions.Prion infection of mouse neurospheres.Prion diseases: from molecular biology to intervention strategies.Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strainsStrain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells.A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.Therapeutic approaches in treating Creutzfeldt-Jakob disease - what does the future hold?Mouse prion protein (PrP) segment 100 to 104 regulates conversion of PrP(C) to PrP(Sc) in prion-infected neuroblastoma cells.COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform.PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells.Prion protein expression in different species: analysis with a panel of new mAbsConversion of truncated and elongated prion proteins into the scrapie isoform in cultured cellsDeposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie.Dissociation of recombinant prion protein fibrils into short protofilaments: implications for the endocytic pathway and involvement of the N-terminal domain.Purification and properties of the cellular prion protein from Syrian hamster brain.
P2860
Q27014940-AC002A64-14C1-4173-9AD3-C1156417B7CEQ28360418-D5677E84-C52B-469D-8459-FEED10DF113FQ28534369-A3666AFA-6B3C-48D9-8562-CCD1204B9808Q28586819-6307508A-48C5-4DAF-9643-AED7974C8FCAQ30570683-8505DF65-9A32-4CE0-BF85-8FCF8DBBF3FDQ30587205-4D2F24E0-18D6-4390-A622-4BA89C4710FEQ30840051-45894CAB-DC36-4A48-A910-F3832B118D74Q31816626-52FF7A2F-C1D7-462B-B67B-29B286EE0BCCQ33558398-CA4757C6-D94B-4524-B80D-83B33C9E09B1Q33719644-F5BEE58F-4E2E-4DCF-9D19-8D0BB90209AAQ33786940-942C3BA9-F317-4BBF-813D-2B880770BC2AQ33860629-0BC0C0FA-570E-4AAB-A3C0-721D2E573718Q33889272-A036A21C-0DA8-449F-8639-8B7988432493Q33925227-5345AA4E-69E0-4F2F-B548-D239A85F161CQ33952879-12D096CC-2DF1-483A-A0C4-EDF50318987DQ34057962-61F7ACF0-436C-4D58-8EEC-E39A08EC82FFQ34069408-8C55F3C3-A955-4A1A-B6A6-B163E09F0592Q34080020-6A72C2D5-1A4C-48BD-95A6-736443FEC9ACQ34090153-50295730-13D5-4929-B0D7-98BAF4DC302EQ34118329-FC21C740-DDA9-4F0D-B7C1-9A8779FA9295Q34301796-0A5913B6-535F-4C36-B5E2-674EAAAB0B44Q34439288-1AF4BD70-46D2-40A5-9CD6-B4B555AB9C80Q34463706-DD8A6B8E-7135-4C88-AD82-8EC2BC9F0FF6Q34520271-1BA5E277-BF12-47C4-B309-0F4821F105CCQ34553074-44A08FED-2841-490B-B013-CAFD6EF70A3BQ34856581-44B3644F-AC62-4F84-ADC0-9ECF1E24A5C2Q34944193-1D989290-7C8F-4B88-914D-7A6E5306BA8BQ35602374-7506F2AE-102C-47C8-B6E2-50B2B197A6C1Q35635237-2A99BE3C-1F09-432B-92D2-88035552858CQ35774144-5FCBA7BF-A399-494E-848C-7EDB821DBBCFQ35899061-2F762080-937F-4333-AEBC-97116607EFADQ35925559-D88F6B6C-E03F-4DF1-AA9F-EF962F4DE321Q35943380-42486043-4C23-4AA8-ABCA-9FC5691EA50CQ36039920-E18439B8-0EA8-4D78-AB6E-F2B76C38F0EAQ36099038-0702CD36-DB36-43BD-A88F-EAD443A314EDQ36222036-C9F35BFF-EE2D-448B-A1A2-8781C979F6CCQ36225344-293BA1B0-0F39-4C9B-A3E8-D4BE88088505Q36245285-2158D6E6-5174-4905-B170-D9C3F27776D7Q36249971-C8AE7D56-E878-45D0-BAEB-AE5EDD76F246Q36277401-CAF0ECF4-D8B2-452B-BF5A-F0E5BEBC3003
P2860
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Scrapie prion proteins accumul ...... ently infected cultured cells.
@ast
Scrapie prion proteins accumul ...... ently infected cultured cells.
@en
type
label
Scrapie prion proteins accumul ...... ently infected cultured cells.
@ast
Scrapie prion proteins accumul ...... ently infected cultured cells.
@en
prefLabel
Scrapie prion proteins accumul ...... ently infected cultured cells.
@ast
Scrapie prion proteins accumul ...... ently infected cultured cells.
@en
P2860
P356
P1476
Scrapie prion proteins accumul ...... ently infected cultured cells.
@en
P2093
A Taraboulos
P2860
P304
P356
10.1083/JCB.110.6.2117
P407
P577
1990-06-01T00:00:00Z