Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling.
about
Mass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein UbiquitylationUbiquitin modificationsOptimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblottingRegulation of NF-κB by ubiquitinationUbiquitination-induced fluorescence complementation (UiFC) for detection of K48 ubiquitin chains in vitro and in live cellsNanobodies and recombinant binders in cell biologyCYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune SignalingUbiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like propertiesTargeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.Assembly and specific recognition of k29- and k33-linked polyubiquitin.Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.Versatile roles of k63-linked ubiquitin chains in trafficking.Ubiquitinated proteins enriched from tumor cells by a ubiquitin binding protein Vx3(A7) as a potent cancer vaccine.The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote MitophagyThe roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's diseaseThe Colossus of ubiquitylation: decrypting a cellular code.Measuring activity in the ubiquitin-proteasome system: from large scale discoveries to single cells analysisA small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaksHepatitis C Virus Proteins Interact with the Endosomal Sorting Complex Required for Transport (ESCRT) Machinery via Ubiquitination To Facilitate Viral Envelopment.Combinational Immunotherapy with Allo-DRibble Vaccines and Anti-OX40 Co-Stimulation Leads to Generation of Cross-Reactive Effector T Cells and Tumor Regression.Proteomic identification of protein ubiquitination events.Selectivity of the ubiquitin-binding modules.Chemical strategies to understand the language of ubiquitin signaling.The TWEAK-Fn14 system as a potential drug target.Ubiquitin-binding domains: mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes.Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins.Role of LAMP1 Binding and pH Sensing by the Spike Complex of Lassa Virus.A Generic Platform for Cellular Screening Against Ubiquitin Ligases.LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications.Sequential multi-molecule delivery using vortex-assisted electroporation.Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest).Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells.Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway.Proteasome-independent functions of lysine-63 polyubiquitination in plants.
P2860
Q26744515-ACCE0947-0A8A-4226-B299-C384C0C5F405Q26751380-49DA9714-A4FA-4FB5-B5E0-86CA1F03477AQ26795621-0567FD7F-AA8B-491C-836C-5A466E522B57Q27024099-BA3DA334-9D1F-44F9-B1E1-6F2FAA973275Q27307830-2D8D7982-0C75-46B5-86B2-513CB7D18E17Q28081411-16CF4D35-5ECF-49B1-9C6A-BDA56F200D83Q28117541-48543C19-E913-41E4-A70C-80BE796DD6B3Q30316288-82F643CA-1503-4489-86A6-38022B4B3869Q33705575-08AF81B3-9392-435F-8E18-5657845B7FA5Q34466293-47DBB221-9DBF-462F-95EC-D6B905FCD3B1Q34622632-3A7754DB-42A0-432E-B5F7-32A2EFF8C637Q34774715-5C0E41F8-6E2F-4FEE-9081-E359897531D5Q35519862-79A4A2BB-DDCB-4BAF-A47F-B2BD0B1E12D0Q36118105-B054A414-AC40-4248-A547-DDBF3805F76EQ36611426-3122EA31-2573-481F-A941-0EA8824300E1Q36660304-2C2EA932-E0F8-4BA3-877B-F6DBC2CEFD4BQ37136216-1629FA87-FAA7-4764-90D5-EFE913BBDEC7Q37168494-603A793A-5590-4380-A533-08A804117357Q37385740-280FF43F-9CEB-4C5F-89F6-B928A53B293FQ37428061-E2D3DDB6-F038-48C3-8EA2-F0FB2E0AB6F2Q37608861-2F6CA50B-D849-4FB3-B86B-EE550CBA1026Q38008504-1F08435E-F06E-4032-8F72-88A5061F8DE2Q38098127-09A92DB8-131B-47B2-9824-2A80F42912FBQ38129961-C755D54F-5BAF-42AB-A93E-70CEF14A3699Q38261255-D67FDADC-0C30-4F4B-A2A7-DE9EC981E1E1Q38724062-CCD60932-3FFF-4FDA-B333-B969C248DDCEQ38736122-357DDE10-2B32-4302-8840-E6B54BF3959CQ38805774-3DBC8361-3487-463C-BFF4-49FE97FFEF89Q38811648-3ED40566-2570-4ED7-9391-59F1F54A35C7Q38913048-929EBD22-0611-4DF9-AE18-2F3126CEB629Q39144821-572535A7-536F-48DE-A5E3-E885AABDDF6BQ41015604-A61237C6-8388-49D9-8A99-3C153C4A9725Q41792409-9E5E576F-BFA4-4E36-9BB7-FDC0BA1E314EQ41900449-73DC5457-D843-44D6-B5A0-084E77ECE059Q42085320-19E8611A-C6FA-4CF2-B952-5A4EB180ACC4Q42732317-F29BD44E-CBA8-4399-A4BA-2D8FDC594F9EQ43248871-7E47EFEB-34FF-43C4-B483-E83B08639312Q43293633-1471B8BD-EF3A-4F38-8AFA-C48802ACEDB6Q46325984-548EFC57-C2AA-40F9-AE2A-05D5ACCBF310Q47342186-5897942A-5EE6-41E2-BD01-D5475002D10A
P2860
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@ast
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@en
type
label
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@ast
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@en
prefLabel
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@ast
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@en
P2093
P2860
P356
P1433
P1476
Polyubiquitin-sensor proteins ...... cellular ubiquitin signaling.
@en
P2093
Eric M Cooper
Francesco Scavone
Jef D Boeke
Joshua J Sims
Lesley A Kane
Richard J Youle
Robert E Cohen
P2860
P2888
P304
P356
10.1038/NMETH.1888
P577
2012-02-05T00:00:00Z