Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells.
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Naïve T Cell Homeostasis Regulated by Stress Responses and TCR SignalingAnimal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside-a Comprehensive ReviewThe pathological and physiological roles of IL-6 amplifier activationThe reverse-direction method links mass experimental data to human diseases.Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice.IL-17-producing T cells can augment autoantibody-induced arthritisSystemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung.Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions.CD4+CD25+ regulatory T cells in autoimmune arthritis.Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditionsGlioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathwayInterleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis.gp130 at the nexus of inflammation, autoimmunity, and cancer.Interleukin 6 in autoimmune and inflammatory diseases: a personal memoirIL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondiiCharacterization of a novel and spontaneous mouse model of inflammatory arthritis.Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine modelCells of the synovium in rheumatoid arthritis. T lymphocytes.The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity.Autoreactive memory CD4+ T lymphocytes that mediate chronic uveitis reside in the bone marrow through STAT3-dependent mechanisms.Variants of Interleukin-7/Interleukin-7 Receptor Alpha are Associated with Both Neuromyelitis Optica and Multiple Sclerosis Among Chinese Han Population in Southeastern ChinaA four-step model for the IL-6 amplifier, a regulator of chronic inflammations in tissue-specific MHC class II-associated autoimmune diseases.SOCS, Inflammation, and Autoimmunity.KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseThe role of all-trans retinoic acid in the biology of Foxp3+ regulatory T cellsPathogenic Transdifferentiation of Th17 Cells Contribute to Perpetuation of Rheumatoid Arthritis during Anti-TNF Treatment.Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis.Ciliary neurotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure.IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis.Integration of B cells and CD8+ T in the protective regulation of systemic epithelial inflammation.Interleukin-6 expands homeostatic space for peripheral T cellsRecent advances in neutralizing the IL-6 pathway in arthritis.Infection and autoimmunity: Lessons of animal models.Lessons from animal models of arthritis over the past decade.Bidirectional Crosstalk between Lymphatic Endothelial Cell and T Cell and Its Implications in Tumor Immunity.The discovery of novel experimental therapies for inflammatory arthritis.Perspectives of the relationship between IL-7 and autoimmune diseases.The gateway theory: bridging neural and immune interactions in the CNS.The expanding role of IL-7 and thymic stromal lymphopoietin as therapeutic target for rheumatoid arthritis.
P2860
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P2860
Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@ast
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@en
type
label
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@ast
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@en
prefLabel
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@ast
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@en
P2093
P2860
P356
P1476
Autoimmune arthritis associate ...... proliferation of CD4+ T cells.
@en
P2093
Daisuke Kamimura
Gui-Hua Jin
Hideyuki Morikawa
Hokuto Kamon
Katsuhiko Ishihara
Masaaki Murakami
Mika Nishihara
Shin-ichiro Sawa
Toshio Hirano
P2860
P304
P356
10.1084/JEM.20052187
P407
P577
2006-05-22T00:00:00Z