Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
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Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) miceHuman T regulatory cell therapy: take a billion or so and call me in the morningRole of Dendritic Cells in the Induction of Lymphocyte ToleranceInsights into type 1 diabetes from the autoimmune polyendocrine syndromesFrom IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokinesA bispecific protein capable of engaging CTLA-4 and MHCII protects non-obese diabetic mice from autoimmune diabetesManipulating regulatory T cells: a promising strategy to treat autoimmunitySpecific immunosuppression with inducible Foxp3-transduced polyclonal T cellsThe role of TNF-α in mice with type 1- and 2- diabetesRetinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cellsA CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis.CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice.Real-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance.Glutamic acid decarboxylase-derived epitopes with specific domains expand CD4(+)CD25(+) regulatory T cells.Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse?Th17 cells and regulatory T cells in elite control over HIV and SIV.Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppressionTGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis.Immune tolerance induction by integrating innate and adaptive immune regulators.In situ prior proliferation of CD4+ CCR6+ regulatory T cells facilitated by TGF-β secreting DCs is crucial for their enrichment and suppression in tumor immunity.Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetopeVirus-specific regulatory T cells ameliorate encephalitis by repressing effector T cell functions from priming to effector stagesAlloantigen-specific regulatory T cells generated with a chimeric antigen receptorDendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner.Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis.Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy.Dendritic-cell-based therapeutic cancer vaccinesHuman CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines.How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic isletsPlasmacytoid dendritic cells are inefficient in activation of human regulatory T cellsAn update on the use of NOD mice to study autoimmune (Type 1) diabetes.Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cellsDendritic cell subsets in health and disease.Hydrogels and scaffolds for immunomodulationLower frequency of CD62L(high) and higher frequency of TNFR2(+) Tregs are associated with inflammatory conditions in type 1 diabetic patients.PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion.A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats
P2860
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P2860
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@ast
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@en
type
label
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@ast
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@en
prefLabel
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@ast
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@en
P2093
P2860
P356
P1476
Dendritic cell-expanded, islet ...... oglycemia in diabetic NOD mice
@en
P2093
Amina Mqadmi
Lucine Petit
Manikkam Suthanthiran
Priscilla Toy
Ralph M Steinman
Svetlana Mojsov
Xiaopan Zuo
Xunrong Luo
P2860
P304
P356
10.1084/JEM.20061631
P407
P577
2007-01-08T00:00:00Z