How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets
about
Transplantation tolerance and its outcome during infections and inflammationInhibition of Autoimmune Diabetes in NOD Mice by miRNA TherapyStructure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T CellsGenetics, pathogenesis and clinical interventions in type 1 diabetesExtrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cellsReal-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance.Vagaries of fluorochrome reporter gene expression in Foxp3+ regulatory T cells.TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cellsHypomethylation at the regulatory T cell-specific demethylated region in CD25hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis.Mature natural killer cells reset their responsiveness when exposed to an altered MHC environmentDifferential control of immune cell homeostasis by Foxp3(+) regulatory T cells in murine peripheral lymph nodes and spleen.Immunomodulation of antigen presenting cells promotes natural regulatory T cells that prevent autoimmune diabetes in NOD mice.Cutting edge: accelerated autoimmune diabetes in the absence of LAG-3A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota.NK cells are not required for spontaneous autoimmune diabetes in NOD mice.Stem cell treatment for type 1 diabetes.Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.Insulin-like growth factor-1 stimulates regulatory T cells and suppresses autoimmune disease.How tolerogenic dendritic cells induce regulatory T cellsRegulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2.IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells.Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouseNatural regulatory T cells in autoimmunity.Dendritic cell control of tolerogenic responses.High-throughput sequencing of islet-infiltrating memory CD4+ T cells reveals a similar pattern of TCR Vβ usage in prediabetic and diabetic NOD miceInfluence of host immunoregulatory genes, ER stress and gut microbiota on the shared pathogenesis of inflammatory bowel disease and Type 1 diabetesAutoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodesViral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay.Regulatory T cells resist virus infection-induced apoptosisUncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.Therapeutic regulatory T cells subvert effector T cell function in inflamed islets to halt autoimmune diabetes.Immunomodulation by gut microbiota: role of Toll-like receptor expressed by T cells.T cell-driven initiation and propagation of autoimmune diabetesMicrobiota and autoimmunity: exploring new avenues.Breakdown in peripheral tolerance in type 1 diabetes in mice and humans
P2860
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P2860
How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
How punctual ablation of regul ...... n within the pancreatic islets
@ast
How punctual ablation of regul ...... n within the pancreatic islets
@en
How punctual ablation of regul ...... n within the pancreatic islets
@nl
type
label
How punctual ablation of regul ...... n within the pancreatic islets
@ast
How punctual ablation of regul ...... n within the pancreatic islets
@en
How punctual ablation of regul ...... n within the pancreatic islets
@nl
prefLabel
How punctual ablation of regul ...... n within the pancreatic islets
@ast
How punctual ablation of regul ...... n within the pancreatic islets
@en
How punctual ablation of regul ...... n within the pancreatic islets
@nl
P2093
P2860
P1433
P1476
How punctual ablation of regul ...... n within the pancreatic islets
@en
P2093
Christophe Benoist
Dan R Littman
Diane Mathis
Markus Feuerer
Yuelei Shen
P2860
P304
P356
10.1016/J.IMMUNI.2009.08.023
P407
P577
2009-10-08T00:00:00Z