Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease.
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Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain agingBreaking boundaries-coagulation and fibrinolysis at the neurovascular interfaceThe pericyte: a forgotten cell type with important implications for Alzheimer's disease?The role of iron-induced fibrin in the pathogenesis of Alzheimer's disease and the protective role of magnesiumRole of fibrinogen in cerebrovascular dysfunction after traumatic brain injuryDevelopmental and pathological angiogenesis in the central nervous systemCerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's diseaseMultiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosisFibrinogen α-chain-derived peptide is upregulated in hippocampus of rats exposed to acute morphine injection and spontaneous alternation testing.Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disordersFibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's diseaseA novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease miceRegional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling.Central nervous system pericytes in health and disease.Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.Epidermal growth factor prevents APOE4-induced cognitive and cerebrovascular deficits in female mice.Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damageADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery.Fibrinogen signal transduction in the nervous system.Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brainAmyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease.Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response.The blood-brain barrier in health and disease.Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people.Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.Anti-amyloid-β-mediated positron emission tomography imaging in Alzheimer's disease mouse brainsTissue plasminogen activator is required for the development of fetal alcohol syndrome in mice.Using In silico LD clumping and meta-analysis of genome-wide datasets as a complementary tool to investigate and validate new candidate biomarkers in Alzheimer's disease.Human apolipoprotein E ɛ4 expression impairs cerebral vascularization and blood-brain barrier function in miceRole of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer's diseaseA fast and reproducible method for albumin isolation and depletion from serum and cerebrospinal fluid.Upregulation of glycolytic enzymes, mitochondrial dysfunction and increased cytotoxicity in glial cells treated with Alzheimer's disease plasma.Quantification of neurovascular protection following repetitive hypoxic preconditioning and transient middle cerebral artery occlusion in miceAPOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain.Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans.Aβ delays fibrin clot lysis by altering fibrin structure and attenuating plasminogen binding to fibrin.High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity.Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeabilityNeurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease.
P2860
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P2860
Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@ast
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@en
type
label
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@ast
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@en
prefLabel
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@ast
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@en
P2093
P2860
P356
P1476
Fibrin deposition accelerates ...... models of Alzheimer's disease.
@en
P2093
Jerry P Melchor
Justin Paul
Sidney Strickland
P2860
P304
P356
10.1084/JEM.20070304
P407
P577
2007-07-30T00:00:00Z