Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus.
about
Effects of anti-Fas antibodies on lymphocytes and other organs: preparation of original and new monoclonal antibodies and amelioration of systemic autoimmune disease.Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contactsCorrection of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice.Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse.Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice.Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide.Precursor B cells for autoantibody production in genomically Fas-intact autoimmune disease are not subject to Fas-mediated immune elimination.Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B.The genetic basis of autoimmune disease in MRL-lpr/lpr mice.Bcl-2 and Fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus?Gld and lpr mice: single gene mutant models for failed self tolerance.Trifluoperazine Inhibits Mesangial Cell Proliferation by Arresting Cell Cycle-Dependent MechanismsApoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation.The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo.Concomitant Disruption of CD4 and CD8 Genes Facilitates the Development of Double Negative αβ TCR+ Peripheral T Cells That Respond Robustly to Staphylococcal Superantigen.Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl‑2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice.
P2860
Q33811734-88EBFEE1-574B-4A0A-83D7-EAEB8D6C993BQ34538716-80F74C38-21D4-45CD-9868-A6D2DC49A0C3Q35108481-DEA60A15-810B-440B-BF70-E34746CAA554Q35834004-CD522AA3-6838-49D8-9FD0-DC134D96E2E6Q36129002-21AC3CD3-D85F-4D08-AC16-15FC53BF8629Q36297378-12E775DD-F2A9-4649-9698-300D53A9C048Q36563392-5629E268-A813-4CC9-898F-C1D56C41C834Q39586822-F225CA94-1954-45FE-B712-582BD14A4B4AQ40393393-D9B3C3D6-EE0D-4B28-975A-39004009B0CFQ40393908-00E22065-3D57-48EE-94E6-379BBA920968Q40635205-FA44B2C6-2523-421F-AB64-BDD29A06C78BQ41113661-A06A400E-684F-4A1B-9A0D-298A3295A598Q42132336-68157916-A568-4644-9609-822961F75DD4Q42944882-895F3018-8522-4F64-AF96-75B2E2E5C703Q51021948-5E151461-ACB8-457B-9439-850B3151C90CQ54119830-15F8BB2B-C8D6-4C1B-A837-EEA634A7CF75
P2860
Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Defect in negative selection i ...... iating in non-lpr host thymus.
@ast
Defect in negative selection i ...... iating in non-lpr host thymus.
@en
type
label
Defect in negative selection i ...... iating in non-lpr host thymus.
@ast
Defect in negative selection i ...... iating in non-lpr host thymus.
@en
prefLabel
Defect in negative selection i ...... iating in non-lpr host thymus.
@ast
Defect in negative selection i ...... iating in non-lpr host thymus.
@en
P2093
P2860
P356
P1476
Defect in negative selection i ...... iating in non-lpr host thymus.
@en
P2093
P2860
P304
P356
10.1084/JEM.173.1.127
P407
P577
1991-01-01T00:00:00Z