Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.
about
Apoptosis of murine neonatal T cells.Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cellsAvoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance.A special repertoire of alpha:beta T cells in neonatal mice.Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus.Acquired Mls-1a-like clonal deletion in Mls-1b miceActivation events during thymic selection.An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7).Mls-1-like superantigen in the MA/MyJ mouse is encoded by a new mammary tumor provirus that is distinct from Mtv-7.Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame proteinFailure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergySuperantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus.In Mls-1a mice, fetal-type beta-gene rearrangements are frequent among self-anergic V beta 6 T cells.B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens.Neonatal deletion and selective expansion of mouse T cells by exposure to rabies virus nucleocapsid superantigen.Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationEssential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal periodInduction of immunological unresponsiveness in vivo and in vitro by conventional and super-antigens in developing and mature T cells.Thymic dendritic cells and B cells: isolation and function.Autospecific gammadelta thymocytes that escape negative selection find sanctuary in the intestineRegulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.Heterogeneity in the CD4 T Cell Compartment and the Variability of Neonatal Immune Responsiveness.Downregulation of T cell receptor expression by CD8(+) lymphocytes in kidney allograftsExogenous Mtv-7 superantigen transgene expression in major histocompatibility complex class II I-E- mice reconstituted with embryonic stem cell-derived hematopoietic stem cells.Mechanisms of autoimmunity in the context of T-cell tolerance: insights from natural and transgenic animal model systems.Tolerance in vivo and in vitro.Alterations in the Thymic Selection Threshold Skew the Self-Reactivity of the TCR Repertoire in Neonates.Apparent bypass of negative selection in CD8+ tumours in CD2-myc transgenic mice.V beta gene repertoire in the aging mouse: a developmental perspective.T-cell repertoires in health and disease.Central tolerance of T cells.A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens.Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus.Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells.
P2860
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P2860
Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Postnatal disappearance of sel ...... development and autoimmunity.
@ast
Postnatal disappearance of sel ...... development and autoimmunity.
@en
type
label
Postnatal disappearance of sel ...... development and autoimmunity.
@ast
Postnatal disappearance of sel ...... development and autoimmunity.
@en
prefLabel
Postnatal disappearance of sel ...... development and autoimmunity.
@ast
Postnatal disappearance of sel ...... development and autoimmunity.
@en
P2093
P2860
P356
P1476
Postnatal disappearance of sel ...... development and autoimmunity.
@en
P2093
Hengartner H
MacDonald HR
Pedrazzini T
Schneider R
Zinkernagel RM
P2860
P304
P356
10.1084/JEM.169.6.2149
P407
P577
1989-06-01T00:00:00Z