Medullary but not cortical thymic epithelial cells present soluble antigens to helper T cells.
about
The Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central ToleranceModulation of Aire regulates the expression of tissue-restricted antigensAutoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytesTSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentationProteases involved in MHC class II antigen presentationCLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing.Differential Response of Mouse Thymic Epithelial Cell Types to Ionizing Radiation-Induced DNA Damage.Prss16 is not required for T-cell development.Diversity in MHC class II antigen presentation.Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection.Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription.Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantationUnmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.Proliferative arrest and rapid turnover of thymic epithelial cells expressing AireMechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblastsPositive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line.Theories and quantification of thymic selection.AIRE activated tissue specific genes have histone modifications associated with inactive chromatinInduction of regulatory T cells from mature T cells by allogeneic thymic epithelial cells in vitro.Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein?Detachment activity but not cytotoxicity induced in a T-cell clone following antigen presentation in the presence of thymic epithelial cells.Production and characterization of mouse thymic epithelial cell clones.Medullary thymic epithelium: a mosaic of epithelial "self"?A novel form of cellular communication among thymic epithelial cells: intercellular calcium wave propagation.Update on Aire and thymic negative selection.
P2860
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P2860
Medullary but not cortical thymic epithelial cells present soluble antigens to helper T cells.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Medullary but not cortical thy ...... le antigens to helper T cells.
@ast
Medullary but not cortical thy ...... le antigens to helper T cells.
@en
type
label
Medullary but not cortical thy ...... le antigens to helper T cells.
@ast
Medullary but not cortical thy ...... le antigens to helper T cells.
@en
prefLabel
Medullary but not cortical thy ...... le antigens to helper T cells.
@ast
Medullary but not cortical thy ...... le antigens to helper T cells.
@en
P2093
P2860
P356
P1476
Medullary but not cortical thy ...... le antigens to helper T cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.175.6.1601
P407
P577
1992-06-01T00:00:00Z