Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes
about
Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequencesSRP keeps polypeptides translocation-competent by slowing translation to match limiting ER-targeting sitesArchitecture, function and prediction of long signal peptides.Regulation of β-cell function by RNA-binding proteins.The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic beta-cells.The 3'-UTR mediates the cellular localization of an mRNA encoding a short plasma membrane protein.Ubiquitin-assisted dissection of protein transport across membranes.The signal recognition particle receptor alpha subunit assembles co-translationally on the endoplasmic reticulum membrane during an mRNA-encoded translation pause in vitro.A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum.Genome scale analysis ofEscherichia coliwith a comprehensive prokaryotic sequence-based biophysical model of translation initiation and elongation.Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens.Identification and analysis of the cleavage site in a signal peptide using SMOTE, dagging, and feature selection methods
P2860
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P2860
Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Discrete nascent chain lengths ...... eins into microsomal membranes
@ast
Discrete nascent chain lengths ...... eins into microsomal membranes
@en
type
label
Discrete nascent chain lengths ...... eins into microsomal membranes
@ast
Discrete nascent chain lengths ...... eins into microsomal membranes
@en
prefLabel
Discrete nascent chain lengths ...... eins into microsomal membranes
@ast
Discrete nascent chain lengths ...... eins into microsomal membranes
@en
P2860
P356
P1476
Discrete nascent chain lengths ...... eins into microsomal membranes
@en
P2093
P2860
P304
P356
10.1083/JCB.121.6.1211
P407
P50
P577
1993-06-01T00:00:00Z