Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
about
Unique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradationTransmembrane transforming growth factor-alpha tethers to the PDZ domain-containing, Golgi membrane-associated protein p59/GRASP55Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growthRepression of bone morphogenetic protein and activin-inducible transcription by Evi-1Transmembrane neuregulins interact with LIM kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognitionRhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog SpitzStructural requirements for the tissue-specific and tissue-general functions of the Caenorhabditis elegans epidermal growth factor LIN-3.Membrane-anchored growth factors, the epidermal growth factor family: beyond receptor ligands.Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factorExtracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice.The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation.The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells.Activator protein 2alpha mediates parathyroid TGF-alpha self-induction in secondary hyperparathyroidism.The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing.Chemical signaling in ciliates.Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme.The proamphiregulin cytoplasmic domain is required for basolateral sorting, but is not essential for constitutive or stimulus-induced processing in polarized Madin-Darby canine kidney cells.Stimulation of cleavage of membrane proteins by calmodulin inhibitors.Biosynthetic processing of neu differentiation factor. Glycosylation trafficking, and regulated cleavage from the cell surface.Phosphorylation-dependent interaction of the cytoplasmic domains of the type I and type II transforming growth factor-beta receptors.Specificity within the EGF family/ErbB receptor family signaling network.The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues.Cysteines 153 and 154 of transmembrane transforming growth factor-alpha are palmitoylated and mediate cytoplasmic protein association.Human keratinocytes and tumor-derived cell lines express alternatively spliced forms of transforming growth factor-alpha mRNA, encoding precursors lacking carboxyl-terminal valine residues.TGF-alpha, EGF, and their cognate EGF receptor are co-expressed with desmin during embryonic, fetal, and neonatal myogenesis in mouse tongue development.Recycling of cell surface pro-transforming growth factor-{alpha} regulates epidermal growth factor receptor activation.
P2860
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P2860
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@ast
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@en
type
label
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@ast
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@en
prefLabel
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@ast
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@en
P2093
P2860
P356
P1476
Association of the transmembrane TGF-alpha precursor with a protein kinase complex.
@en
P2093
P2860
P304
P356
10.1083/JCB.125.4.903
P407
P577
1994-05-01T00:00:00Z