Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme.
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TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cellsEvidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1Trafficking regulation of proteins in Alzheimer's diseaseAPP processing in Alzheimer's diseaseA Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous SystemsMetalloprotease disintegrin-mediated ectodomain shedding of EGFR ligands promotes intestinal epithelial restitutionInvolvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytesEssential role for ADAM19 in cardiovascular morphogenesisDistinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligandsUncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Shooting from the hip: spatial control of signal release by intracellular waves.Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signallingChemotherapy-induced activation of ADAM-17: a novel mechanism of drug resistance in colorectal cancer.Long-range signal transmission in autocrine relays.ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.TACE is required for the activation of the EGFR by TGF-alpha in tumorsMetalloprotease ADAM10 is required for Notch1 site 2 cleavage.Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.Potential role for ADAM15 in pathological neovascularization in mice.Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site.Anti-microRNA-222 (anti-miR-222) and -181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal.Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancerADAM proteases, ErbB pathways and cancer.Meprinα transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migrationGlutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neuronsSignal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk.ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively.Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery.Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.The Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer's Disease.Inhibition of doxorubicin-induced HER3-PI3K-AKT signalling enhances apoptosis of ovarian cancer cells.Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44Amino-terminal TACE prodomain attenuates TNFR2 cleavage independently of the cysteine switch.Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor.MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17.
P2860
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P2860
Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Metalloprotease-dependent prot ...... actor-alpha-converting enzyme.
@en
type
label
Metalloprotease-dependent prot ...... actor-alpha-converting enzyme.
@en
prefLabel
Metalloprotease-dependent prot ...... actor-alpha-converting enzyme.
@en
P2093
P2860
P356
P1476
Metalloprotease-dependent prot ...... actor-alpha-converting enzyme.
@en
P2093
A Merlos-Suárez
S Ruiz-Paz
P2860
P304
48510-48517
P356
10.1074/JBC.M103488200
P407
P577
2001-10-12T00:00:00Z