Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets.

Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets.

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http://www.wikidata.org/entity/Q36234829
Potential roles of GPR120 and its agonists in the management of diabetesComparison of the efficacy of sitagliptin and glimepiride dose-up in Japanese patients with type 2 diabetes poorly controlled by sitagliptin and glimepiride in combination.Regulation of iNOS gene transcription by IL-1β and IFN-γ requires a coactivator exchange mechanism.Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling.Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferationMinireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Role of COX-2/mPGES-1/prostaglandin E2 cascade in kidney injury.Diabetes Associated Metabolomic Perturbations in NOD Mice.COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes.Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremiaThe PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male MiceProstaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.The COX-2/PGE2/EP3/Gi/o/cAMP/GSIS Pathway in the Islet: The Beat Goes On.
P2860

Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets.

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http://www.wikidata.org/entity/Q36234829
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@ast
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@en
type
label
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@ast
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@en
prefLabel
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@ast
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Cyclooxygenase-2, not microsom ...... ecretion in pancreatic islets.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932