Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation
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Tissue-resident macrophagesGene therapy on the moveMyeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal diseaseRemote control of induced dopaminergic neurons in parkinsonian rats.Inefficient clearance of myelin debris by microglia impairs remyelinating processesTherapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophyOpen issues in Mucopolysaccharidosis type I-HurlerThe role of microglia in human disease: therapeutic tool or target?Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.Origin, development, and homeostasis of tissue-resident macrophages.Gene therapy for lysosomal storage disorders: a good start.Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis.Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier.Long-term outcomes after allogeneic hematopoietic stem cell transplantation for metachromatic leukodystrophy: the largest single-institution cohort report.Leukocyte telomere length and hippocampus volume: a meta-analysis.Brain endothelial dysfunction in cerebral adrenoleukodystrophy.Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenationNew tools for studying microglia in the mouse and human CNS.Origin and differentiation of microglia.Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophagesThe potential for genetically altered microglia to influence glioma treatment.Origin of microglia: current concepts and past controversies.Outcome of Early Juvenile Onset Metachromatic Leukodystrophy After Unrelated Cord Blood Transplantation: A Case Series and Review of the Literature.Mitochondrial Neurogastrointestinal Encephalomyopathy Caused by Thymidine Phosphorylase Enzyme Deficiency: From Pathogenesis to Emerging Therapeutic Options.Microglial Interferon Signaling and White Matter.Friend or Foe? Resident Microglia vs Bone Marrow-Derived Microglia and Their Roles in the Retinal Degeneration.Perspective on innovative therapies for globoid cell leukodystrophy.Hematopoietic Stem Cell Gene Therapy for Storage Disease: Current and New Indications.Busulfan conditioning enhances engraftment of hematopoietic donor-derived cells in the brain compared with irradiation.Busulfan as a myelosuppressive agent for generating stable high-level bone marrow chimerism in mice.Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance.Microglial recruitment of IL-1β-producing monocytes to brain endothelium causes stress-induced anxiety.Bone Marrow-Derived Cell Accumulation in the Spinal Cord Is Independent of Peripheral Mobilization in a Mouse Model of Amyotrophic Lateral Sclerosis.Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells.Splitting the "Unsplittable": Dissecting Resident and Infiltrating Macrophages in Experimental Autoimmune Encephalomyelitis.HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?Effectiveness of Early Hematopoietic Stem Cell Transplantation in Preventing Neurocognitive Decline in Mucopolysaccharidosis Type II: A Case Series.
P2860
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P2860
Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Brain conditioning is instrume ...... etic stem cell transplantation
@ast
Brain conditioning is instrume ...... etic stem cell transplantation
@en
type
label
Brain conditioning is instrume ...... etic stem cell transplantation
@ast
Brain conditioning is instrume ...... etic stem cell transplantation
@en
prefLabel
Brain conditioning is instrume ...... etic stem cell transplantation
@ast
Brain conditioning is instrume ...... etic stem cell transplantation
@en
P2093
P2860
P50
P356
P1476
Brain conditioning is instrume ...... etic stem cell transplantation
@en
P2093
Alessandra Biffi
Alessandro Nonis
Alessio Palini
Clelia di Serio
Rita Milazzo
Stefania Merella
Tiziana Plati
P2860
P304
15018-15023
P356
10.1073/PNAS.1205858109
P407
P577
2012-08-23T00:00:00Z