Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype.
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Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptorEndogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cellsPeripheral cannabinoid receptor, CB2, regulates bone mass.osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationTransgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotypeRegulation of postnatal bone homeostasis by TGFβDoxorubicin-mediated bone loss in breast cancer bone metastases is driven by an interplay between oxidative stress and induction of TGFβEstrogen regulation of immune cell bone interactionsEndothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activityAge-related adaptation of bone-PDL-tooth complex: Rattus-Norvegicus as a model systemGrowth defect in Grg5 null mice is associated with reduced Ihh signaling in growth platesBone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailabilityAnti-transforming growth factor ß antibody treatment rescues bone loss and prevents breast cancer metastasis to boneNFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.Demonstration of the interaction of transforming growth factor beta 2 and type X collagen using a modified tandem affinity purification tag.Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearingTargeted expression of csCSF-1 in op/op mice ameliorates tooth defectsLef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific mannerAn age-dependent interaction with leptin unmasks ghrelin's bone-protective effectsMicroRNA miR-23a cluster promotes osteocyte differentiation by regulating TGF-β signalling in osteoblasts.Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta.TGF-β1 as possible link between loss of bone mineral density and chronic inflammation.Parathyroid hormone receptor signaling induces bone resorption in the adult skeleton by directly regulating the RANKL gene in osteocytes.Central IL-1 receptor signaling regulates bone growth and massEnhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone.Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL productionTGF-beta regulates the mechanical properties and composition of bone matrix.Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?A bisphosphonate that does not affect osteoclasts prevents osteoblast and osteocyte apoptosis and the loss of bone strength induced by glucocorticoids in mice.The host microenvironment influences prostate cancer invasion, systemic spread, bone colonization, and osteoblastic metastasis.Secreted phosphoprotein 24 kD (Spp24) and Spp14 affect TGF-β induced bone formation differentlyMesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice.Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice.Proteomics analysis of the zebrafish skeletal extracellular matrix.PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer.Photothermal stress triggered by near infrared-irradiated carbon nanotubes promotes bone deposition in rat calvarial defects.The mammalian lectin galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice.Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.
P2860
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P2860
Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@ast
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@en
type
label
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@ast
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@en
prefLabel
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@ast
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@en
P2860
P356
P1476
Increased expression of TGF-be ...... n osteoporosis-like phenotype.
@en
P2093
A Erlebacher
P2860
P304
P356
10.1083/JCB.132.1.195
P407
P577
1996-01-01T00:00:00Z