Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E.
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PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitroANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modificationEstrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cellsTamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selectionEstrogen regulation of cyclin E2 requires cyclin D1 but not c-MycCyclins: roles in mitogenic signaling and oncogenic transformationRegulation of GREB1 transcription by estrogen receptor alpha through a multipartite enhancer spread over 20 kb of upstream flanking sequencesAmplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancersDisruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesisRSK in tumorigenesis: connections to steroid signaling.Pathways to tamoxifen resistance.A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen.Luminal breast cancer cell lines overexpressing ZNF703 are resistant to tamoxifen through activation of Akt/mTOR signalingEnhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancerIdentification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer.ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways.HEXIM1 regulates 17beta-estradiol/estrogen receptor-alpha-mediated expression of cyclin D1 in mammary cells via modulation of P-TEFbGenistein inhibits the proliferation and differentiation of MCF-7 and 3T3-L1 cells via the regulation of ERα expression and induction of apoptosisHigh expression of cyclin D1 is associated to high proliferation rate and increased risk of mortality in women with ER-positive but not in ER-negative breast cancers.FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistancePBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer.Palbociclib (PD 0332991) : targeting the cell cycle machinery in breast cancer.Co-expression of estrogen receptor-alpha and targets of estrogen receptor action in proliferating monkey mammary epithelial cells.Effects of an Indolocarbazole-Derived CDK4 Inhibitor on Breast Cancer CellsPlacental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortexCyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients.Effects of celecoxib and ly117018 combination on human breast cancer cells in vitro.MYC and Breast Cancer.Cadmium mimics estrogen-driven cell proliferation and prolactin secretion from anterior pituitary cells.Anti-cancer effects of Grailsine-Al-glycoside isolated from Rhizoma SparganiiUp-regulation of cyclin E in breast cancer via estrogen receptor pathway.N-myc downstream-regulated gene 2, a novel estrogen-targeted gene, is involved in the regulation of Na+/K+-ATPaseFunctional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation.Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsivenessModulation of expression of heat shock proteins and apoptosis by Flueggea leucopyrus (Willd) decoction in three breast cancer phenotypes.Effects of Combination of Estradiol with Selective Progesterone Receptor Modulators (SPRMs) on Human Breast Cancer Cells In Vitro and In Vivo.PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells.Cryptotanshinone inhibits breast cancer cell growth by suppressing estrogen receptor signalingOvercoming Endocrine Resistance in Hormone-Receptor Positive Advanced Breast Cancer-The Emerging Role of CDK4/6 InhibitorsG0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program.
P2860
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P2860
Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E.
@ast
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E.
@en
type
label
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E.
@ast
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E.
@en
prefLabel
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E.
@ast
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E.
@en
P2093
P356
P1476
Downstream targets of growth f ...... c-Myc, cyclin D1 and cyclin E
@en
P2093
Catriona M McNeil
Elizabeth A Musgrove
Robert L Sutherland
P304
P356
10.1677/ERC.1.00993
P478
12 Suppl 1
P577
2005-07-01T00:00:00Z