YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.
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PTPN14 is required for the density-dependent control of YAP1The Regulatory Role of KIBRA and PTPN14 in Hippo Signaling and BeyondEsophageal cancer stem cells and implications for future therapeuticsThe two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentTargeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer TherapyThe Hippo signaling pathway in stem cell biology and cancerThe role of the Hippo pathway in human disease and tumorigenesisSELPHI: correlation-based identification of kinase-associated networks from global phospho-proteomics data sets.The Hippo pathway in disease and therapy: cancer and beyondPTPN14 forms a complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic functionYAP regulates cell proliferation, migration, and steroidogenesis in adult granulosa cell tumors.The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity.The Hippo pathway regulates homeostatic growth of stem cell niche precursors in the Drosophila ovaryGenetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells.Up-regulation of the Hippo pathway effector TAZ renders lung adenocarcinoma cells harboring EGFR-T790M mutation resistant to gefitinib.Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.Endosomal regulation of contact inhibition through the AMOT:YAP pathway.Significant association of oncogene YAP1 with poor prognosis and cetuximab resistance in colorectal cancer patients.Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitisBayesian model of signal rewiring reveals mechanisms of gene dysregulation in acquired drug resistance in breast cancerYAP activation protects urothelial cell carcinoma from treatment-induced DNA damage.Proteomic approaches to the study of papillomavirus-host interactions.Yes associated protein is a poor prognostic factor in well-differentiated lung adenocarcinomaVerteporfin, a suppressor of YAP-TEAD complex, presents promising antitumor properties on ovarian cancerInhibition of YAP suppresses CML cell proliferation and enhances efficacy of imatinib in vitro and in vivo.Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformationHigh-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.Integration of mechanical and chemical signals by YAP and TAZ transcription coactivatorsYAP promotes erlotinib resistance in human non-small cell lung cancer cells.CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression.The Hippo signaling pathway provides novel anti-cancer drug targets.Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway.The Hippo pathway: regulators and regulations.Genetic alterations of protein tyrosine phosphatases in human cancers.The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.The Hippo pathway in chemotherapeutic drug resistance.The regulation and function of YAP transcription co-activator.Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration.Tyrosine phosphorylation of WW proteins.
P2860
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P2860
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@ast
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@en
type
label
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@ast
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@en
prefLabel
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@ast
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@en
P2093
P2860
P356
P1433
P1476
YAP modifies cancer cell sensi ...... otein tyrosine phosphatase 14.
@en
P2093
I Nagatomo
M I Greene
P2860
P2888
P304
P356
10.1038/ONC.2012.231
P407
P577
2012-06-11T00:00:00Z
P5875
P6179
1006182819