Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
about
Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy.Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia.Long-Term Safety and Efficacy of Subcutaneous Methylnaltrexone in Patients with Opioid-Induced Constipation and Chronic Noncancer Pain: A Phase 3, Open-Label Trial.Insights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance.Randomized, Double-Blind Trial of Oral Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain.Role of central versus peripheral opioid system in antinociceptive and anti-inflammatory effect of botulinum toxin type A in trigeminal region.The Evolving Role of Long-Term Pharmacotherapy for Opioid-Induced Constipation in Patients Being Treated for Noncancer Pain.Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadoneOral methylnaltrexone does not negatively impact analgesia in patients with opioid-induced constipation and chronic noncancer pain
P2860
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P2860
Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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name
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@ast
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@en
type
label
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@ast
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@en
prefLabel
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@ast
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@en
P2093
P2860
P356
P1476
Analysis of opioid-mediated an ...... ts with chronic noncancer pain
@en
P2093
Andrew C Barrett
Craig Paterson
Darren M Brenner
Enoch Bortey
Lynn R Webster
William P Forbes
P2860
P304
P356
10.2147/JPR.S88203
P577
2015-10-30T00:00:00Z