Aggregation as a determinant of protein fate in post-Golgi compartments: role of the luminal domain of furin in lysosomal targeting
about
Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furinMisfolding diverts CFTR from recycling to degradation: quality control at early endosomesCharacteristics of the interaction between Hsc70 and the transferrin receptor in exosomes released during reticulocyte maturationResponse of an integral granule membrane protein to changes in pHThe ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.An atypical sorting determinant in the cytoplasmic domain of P-selectin mediates endosomal sortingPrions and retroviruses: an endosomal rendezvous?Selective processing and metabolism of disease-causing mutant prion proteins.Basolateral sorting of furin in MDCK cells requires a phenylalanine-isoleucine motif together with an acidic amino acid cluster.Quality control for unfolded proteins at the plasma membrane.Manganese induces oligomerization to promote down-regulation of the intracellular trafficking receptor used by Shiga toxin.Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients.Identification of a pH sensor in the furin propeptide that regulates enzyme activationSecretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems.Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation.A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis.Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathwaysCOOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments.Induced oligomerization targets Golgi proteins for degradation in lysosomes.Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization.Human herpesvirus 7 U21 tetramerizes to associate with class I major histocompatibility complex molecules.Functional Rescue of F508del-CFTR Using Small Molecule CorrectorsLumenal and transmembrane domains play a role in sorting type I membrane proteins on endocytic pathways.Trafficking of varicella-zoster virus glycoprotein gI: T(338)-dependent retention in the trans-Golgi network, secretion, and mannose 6-phosphate-inhibitable uptake of the ectodomain.A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation.Activation and routing of membrane-tethered prohormone convertases 1 and 2.Strategies for recombinant Furin employment in a biotechnological process: complete target protein precursor cleavage.Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid raftsAccess of a membrane protein to secretory granules is facilitated by phosphorylation.Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin.Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers.Different degradation pathways for heterologous glycoproteins in yeast.Functional analysis of a Golgi-localized Kex2p-like protease in tobacco suspension culture cells
P2860
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P2860
Aggregation as a determinant of protein fate in post-Golgi compartments: role of the luminal domain of furin in lysosomal targeting
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Aggregation as a determinant o ...... f furin in lysosomal targeting
@ast
Aggregation as a determinant o ...... f furin in lysosomal targeting
@en
type
label
Aggregation as a determinant o ...... f furin in lysosomal targeting
@ast
Aggregation as a determinant o ...... f furin in lysosomal targeting
@en
prefLabel
Aggregation as a determinant o ...... f furin in lysosomal targeting
@ast
Aggregation as a determinant o ...... f furin in lysosomal targeting
@en
P2860
P356
P1476
Aggregation as a determinant o ...... f furin in lysosomal targeting
@en
P2093
P2860
P304
P356
10.1083/JCB.139.7.1735
P407
P577
1997-12-01T00:00:00Z