Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation.
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NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growthGene targeting studies begin to reveal the function of neurofilament proteinsMyosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament densityDistal to proximal development of peripheral nerves requires the expression of neurofilament heavySelective solubilization of high-molecular-mass neurofilament subunit during nerve regenerationDisruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunitsEtifoxine improves peripheral nerve regeneration and functional recovery.Neurofilaments form a highly stable stationary cytoskeleton after reaching a critical level in axons.Characterization of the phosphorylation sites of the squid (Loligo pealei) high-molecular-weight neurofilament protein from giant axon axoplasm.Intermediate filaments: a historical perspectiveAltered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS.Reduced number of unmyelinated sensory axons in peripherin null mice.The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament networkTargeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethalityAxonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie Tooth neuropathy.Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1Dissociation of Axonal Neurofilament Content from Its Transport RateNeurofilament Phosphorylation during Development and Disease: Which Came First, the Phosphorylation or the Accumulation?A self-consistent field analysis of the neurofilament brush with amino-acid resolution.Failure of lower motor neuron radial outgrowth precedes retrograde degeneration in a feline model of spinal muscular atrophy.Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration.Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A.The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate.Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylationAge-related atrophy of motor axons in mice deficient in the mid-sized neurofilament subunit.A novel perspective on tau in Alzheimer's disease.Axonal regeneration and neuroinflammation: roles for the translocator protein 18 kDa.Neurofilament phosphorylation and their proline-directed kinases in health and disease.Neurofilaments and Neurofilament Proteins in Health and Disease.Phosphorylation of the head domain of neurofilament protein (NF-M): a factor regulating topographic phosphorylation of NF-M tail domain KSP sites in neurons.Neurofilament cytoskeleton disruption does not modify accumulation of trophic factor mRNA.Alterations in neurofilament protein(s) in human leprous nerves: morphology, immunohistochemistry and Western immunoblot correlative study.
P2860
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P2860
Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@ast
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@en
type
label
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@ast
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@en
prefLabel
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@ast
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@en
P2093
P2860
P356
P1476
Neurofilament-dependent radial ...... (NF-H) or its phosphorylation.
@en
P2093
D W Cleveland
M K Houseweart
T L Williamson
T O Crawford
P2860
P304
P356
10.1083/JCB.143.1.171
P407
P577
1998-10-01T00:00:00Z