Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. - Wikidata - wikimedia - TriplyDB

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

http://www.wikidata.org/entity/Q36255622

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Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation Role of p53/FAK association and p53Ser46 phosphorylation in staurosporine-mediated apoptosis: wild type versus mutant p53-R175H MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis Characterization of integrin engagement during defined human embryonic stem cell culture Regulation of focal adhesion kinase by a novel protein inhibitor FIP200 Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals Differential regulation of cell motility and invasion by FAK The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase.GIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 Motifs Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics Plasma membrane-associated pY397FAK is a marker of cytotrophoblast invasion in vivo and in vitro Purification, molecular cloning and mechanism of action of graminelysin I, a snake-venom-derived metalloproteinase that induces apoptosis of human endothelial cells The de-adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state?Rat embryo fibroblasts require both the cell-binding and the heparin-binding domains of fibronectin for survival Energetic determinants of tyrosine phosphorylation of focal adhesion proteins during hypoxia/reoxygenation of kidney proximal tubules Ligand bound beta1 integrins inhibit procaspase-8 for mediating cell adhesion-mediated drug and radiation resistance in human leukemia cells FAK+ and PYK2/CAKbeta, two related tyrosine kinases highly expressed in the central nervous system: similarities and differences in the expression pattern The SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase.Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase.The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.Regulation of focal adhesion targeting and inhibitory functions of the FAK related protein FRNK using a novel estrogen receptor "switch".Expression of focal adhesion kinase in normal and pathologic human prostate tissues.Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal.Integrins regulate the apoptotic response to DNA damage through modulation of p53 Focal adhesion kinase and endothelial cell apoptosis.Noise induced changes in the expression of p38/MAPK signaling proteins in the sensory epithelium of the inner ear.Translocation of full-length Bid to mitochondria during anoikis.Protein tyrosine phosphatase-dependent proteolysis of focal adhesion complexes in endothelial cell apoptosis.Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis.Homozygous mutation of focal adhesion kinase in embryonic stem cell derived neurons: normal electrophysiological and morphological properties in vitro.B cell receptor signaling involves physical and functional association of FAK with Lyn and IgM.Increased expression of focal adhesion kinase in thyroid cancer: immunohistochemical study.

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P2860

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

http://www.wikidata.org/entity/Q36255622

description

1998 nî lūn-bûn

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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1998年论文

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1998年论文

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name

Extracellular matrix survival ...... ppress p53-mediated apoptosis.

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Extracellular matrix survival ...... ppress p53-mediated apoptosis.

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type

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Extracellular matrix survival ...... ppress p53-mediated apoptosis.

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Extracellular matrix survival ...... ppress p53-mediated apoptosis.

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prefLabel

Extracellular matrix survival ...... ppress p53-mediated apoptosis.

@ast

Extracellular matrix survival ...... ppress p53-mediated apoptosis.

@en

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Extracellular matrix survival ...... uppress p53-mediated apoptosis

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P2093

C H Damsky

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D D Schlaepfer

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E A Almeida

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P Dazin

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S Aizawa

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P2860

Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

Integrins: versatility, modulation, and signaling in cell adhesion

p53, the cellular gatekeeper for growth and division

Apoptosis in the pathogenesis and treatment of disease

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

Cleavage of focal adhesion kinase by caspases during apoptosis

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein.

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2

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143

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extracellular matrix

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2132850

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