Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.

Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.

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http://www.wikidata.org/entity/Q36256395
The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamilyInhibition of human alpha1E subunit-mediated ca2+ channels by the antipsychotic agent chlorpromazineNeuronal nicotinic receptors: from protein structure to functionThe functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis.Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazineArrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes.Dynamic structural investigations on the torpedo nicotinic acetylcholine receptor by time-resolved photoaffinity labeling.Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand.Functional domains of the nicotinic acetylcholine receptor.[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel.Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor.The noncompetitive blocker [(3)H]chlorpromazine labels segment M2 but not segment M1 of the nicotinic acetylcholine receptor alpha-subunit.Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study.
P2860

Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.

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http://www.wikidata.org/entity/Q36256395
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1984 nî lūn-bûn
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Time-resolved photolabeling by ...... sed ion channel conformations.
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Time-resolved photolabeling by ...... sed ion channel conformations.
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Time-resolved photolabeling by ...... sed ion channel conformations.
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Time-resolved photolabeling by ...... sed ion channel conformations.
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Time-resolved photolabeling by ...... sed ion channel conformations.
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Time-resolved photolabeling by ...... sed ion channel conformations.
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Time-resolved photolabeling by ...... sed ion channel conformations.
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932