Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.
about
The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamilyInhibition of human alpha1E subunit-mediated ca2+ channels by the antipsychotic agent chlorpromazineNeuronal nicotinic receptors: from protein structure to functionThe functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis.Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazineArrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes.Dynamic structural investigations on the torpedo nicotinic acetylcholine receptor by time-resolved photoaffinity labeling.Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand.Functional domains of the nicotinic acetylcholine receptor.[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel.Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor.The noncompetitive blocker [(3)H]chlorpromazine labels segment M2 but not segment M1 of the nicotinic acetylcholine receptor alpha-subunit.Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study.
P2860
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P2860
Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
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1984年学术文章
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1984年学术文章
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1984年学术文章
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1984年學術文章
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name
Time-resolved photolabeling by ...... sed ion channel conformations.
@ast
Time-resolved photolabeling by ...... sed ion channel conformations.
@en
type
label
Time-resolved photolabeling by ...... sed ion channel conformations.
@ast
Time-resolved photolabeling by ...... sed ion channel conformations.
@en
prefLabel
Time-resolved photolabeling by ...... sed ion channel conformations.
@ast
Time-resolved photolabeling by ...... sed ion channel conformations.
@en
P2860
P356
P1476
Time-resolved photolabeling by ...... sed ion channel conformations.
@en
P2093
Changeux JP
Heidmann T
P2860
P304
P356
10.1073/PNAS.81.6.1897
P407
P577
1984-03-01T00:00:00Z