CHIP activates HSF1 and confers protection against apoptosis and cellular stress
about
p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylaseCHIP interacts with heat shock factor 1 during heat stressCHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradationIdentification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylationBAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorHsp70 chaperones: cellular functions and molecular mechanismAkt and CHIP coregulate tau degradation through coordinated interactionsCHIP: A new modulator of human malignant disordersNuclear FAK: a new mode of gene regulation from cellular adhesionsROS stress resets circadian clocks to coordinate pro-survival signalsInteractions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymesThe Hsp70/90 cochaperone, Sti1, suppresses proteotoxicity by regulating spatial quality control of amyloid-like proteins.A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclaseAn androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP)Regulation of the cytoplasmic quality control protein degradation pathway by BAG2CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic responseIdentification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxiaCHIP regulates AKT/FoxO/Bim signaling in MCF7 and MCF10A cellsUbe2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIPThe E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance.Chaperone functions of the E3 ubiquitin ligase CHIP.Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIPFacilitating Akt clearance via manipulation of Hsp70 activity and levels.The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor TurnoverThe Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative DiseasesOn mechanisms that control heat shock transcription factor activity in metazoan cells.Carboxyl terminus of Hsp70-interacting protein regulation of osteoclast formation in mice through promotion of tumor necrosis factor receptor-associated factor 6 protein degradation.C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis.A caspase cleaved form of tau is preferentially degraded through the autophagy pathway.Getting folded: chaperone proteins in muscle development, maintenance and disease.The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3mTORC1 links protein quality and quantity control by sensing chaperone availability.Trehalose improves human fibroblast deficits in a new CHIP-mutation related ataxia.Minireview: hey U(PS): metabolic and proteolytic homeostasis linked via AMPK and the ubiquitin proteasome system.Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulationHaploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments.
P2860
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P2860
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@ast
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@en
type
label
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@ast
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@en
prefLabel
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@ast
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@en
P2093
P2860
P356
P1433
P1476
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
@en
P2093
Cam Patterson
Chunlian Zhang
Douglas Cyr
Holly McDonough
Hui-Hua Li
Len Neckers
Nageswara Madamanchi
Ryan A Whaley
Virginia Godfrey
P2860
P304
P356
10.1093/EMBOJ/CDG529
P407
P577
2003-10-01T00:00:00Z