The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells.
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M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctionsalpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsThe FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-cateninAn ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organizationSpecificity in Ras and Rap signalingCingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosinThe junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilinOSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytesThe Ras target AF-6 is a substrate of the fam deubiquitinating enzymeAn atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludinNanoparticle based insulin delivery system: the next generation efficient therapy for Type 1 diabetesAlterations of the apical junctional complex and actin cytoskeleton and their role in colorectal cancer progressionSynaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationThe Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cellsInteraction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludinThe deubiquitinating enzyme Fam interacts with and stabilizes beta-cateninThermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamilyThe tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-BClaudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray studyRequirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesisTwo cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteinsA multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin.The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brainNectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interactionIdentification of genes periodically expressed in the human cell cycle and their expression in tumorsAssociation between segments of zonula occludens proteins: live-cell FRET and mass spectrometric analysis.Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cellsAMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens.Fractionation of the epithelial apical junctional complex: reassessment of protein distributions in different substructuresThe PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled.PICK-1: a scaffold protein that interacts with Nectins and JAMs at cell junctions.The LIM domain protein Lmo2 binds to AF6, a translocation partner of the MLL oncogene.Cell adhesion, polarity, and epithelia in the dawn of metazoans.Afadin is localized at cell-cell contact sites in mesangial cells and regulates migratory polarity.Arecoline induced disruption of expression and localization of the tight junctional protein ZO-1 is dependent on the HER 2 expression in human endometrial Ishikawa cells.ZO-1 and ZO-2 are required for extra-embryonic endoderm integrity, primitive ectoderm survival and normal cavitation in embryoid bodies derived from mouse embryonic stem cells.
P2860
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P2860
The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@ast
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@en
type
label
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@ast
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@en
prefLabel
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@ast
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@en
P2093
P2860
P356
P1476
The Ras target AF-6 interacts ...... junctions in epithelial cells.
@en
P2093
A Mizoguchi
K Kaibuchi
T Yamamoto
Y Matsuura
P2860
P304
P356
10.1083/JCB.139.3.785
P407
P577
1997-11-01T00:00:00Z