Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface.
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Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA ReceptorsPhotoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding Sites.The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries.Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics.Enantiomeric barbiturates bind distinct inter- and intrasubunit binding sites in a nicotinic acetylcholine receptor (nAChR).Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy.General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type A Receptors (GABAARs).Binding site opening by loop C shift and chloride ion-pore interaction in the GABAA receptor model.
P2860
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P2860
Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@ast
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@en
type
label
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@ast
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@en
prefLabel
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@ast
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@en
P2093
P2860
P356
P1476
Positive and Negative Alloster ...... Domain at the γ+-β- Interface.
@en
P2093
David C Chiara
Jonathan B Cohen
Karol S Bruzik
Keith W Miller
Pavel Y Savechenkov
Rooma Desai
Selwyn S Jayakar
Xiaojuan Zhou
P2860
P304
23432-23446
P356
10.1074/JBC.M115.672006
P407
P577
2015-07-30T00:00:00Z