Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.
about
Functional interrogation of non-coding DNA through CRISPR genome editing.Molecular basis of β thalassemia and potential therapeutic targets.Technical considerations for the use of CRISPR/Cas9 in hematology research.An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility.Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies.Concise Review: Epigenetic Regulation of Hematopoiesis: Biological Insights and Therapeutic Applications.A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression.Am I ready for CRISPR? A user's guide to genetic screens.Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.Genome-wide association studies of cancer: current insights and future perspectives.Dissecting super-enhancer hierarchy based on chromatin interactions.CRISPR-based methods for high-throughput annotation of regulatory DNA.Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.The Current State and Future of CRISPR-Cas9 gRNA Design Tools
P2860
Q36306820-683DD7E2-3D10-4AEF-9A24-FCEA25141820Q39399184-35AE48E4-F650-45CD-B024-1354D21D7555Q40113930-25E57F43-901E-4F9B-B738-BCC4FB1D7569Q40132263-6C167B1C-752B-478A-8976-D45E88BC23B4Q45875308-49D40ECF-5F98-4515-8483-AB2109B1A9C7Q47147613-BC051731-AD64-45C3-8B8B-90425683EC6EQ47261747-0933136F-6339-4FDD-B2CE-470AC2BB9025Q47281660-EB1D9187-2439-4884-BEA6-ECAA3F82D686Q47327388-5B487DC9-1FAA-43C3-BCEA-9E72F8BAB936Q47356354-69980150-14D3-4B08-9311-BA69517226B7Q47594697-E1D320A6-DC90-4A25-A65D-4BEF08EE9CA6Q47594709-CD0F7B12-8700-4F93-8A82-DE10EBC5C945Q47900293-0C68DD1B-637A-43F8-9DA2-096EDB0966C3Q51418242-9610D2CF-1310-42F5-8271-6FB270EB6CB7Q52430572-DCA039D6-4495-44D4-BDE4-94B48F513957Q52686206-03BCF3E9-7C2A-4073-8F89-4E2B1E20883CQ52690497-39A87E0C-3AC9-4399-AAD2-46496646F769Q57176284-0D8B6A0C-CC6E-487E-B098-C6B2844D8651
P2860
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh
2017年學術文章
@zh-hant
name
Variant-aware saturating mutag ...... ents at trait-associated loci.
@ast
Variant-aware saturating mutag ...... ents at trait-associated loci.
@en
type
label
Variant-aware saturating mutag ...... ents at trait-associated loci.
@ast
Variant-aware saturating mutag ...... ents at trait-associated loci.
@en
prefLabel
Variant-aware saturating mutag ...... ents at trait-associated loci.
@ast
Variant-aware saturating mutag ...... ents at trait-associated loci.
@en
P2093
P2860
P50
P356
P1433
P1476
Variant-aware saturating mutag ...... ments at trait-associated loci
@en
P2093
Abdullah Kutlar
Austen J Needleman
Carlo Brugnara
Colin McKenzie
Daniel E Bauer
Diane D Chen
Emily N Stern
Frédéric Galactéros
Guillaume Lettre
Guo-Cheng Yuan
P2860
P2888
P304
P356
10.1038/NG.3793
P407
P577
2017-02-20T00:00:00Z