Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction
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Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytesLyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cellsThe c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-MplBinding of src-like kinases to the beta-subunit of the interleukin-3 receptor.The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase.The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line.Mechanisms of T-cell activation by human T-cell lymphotropic virus type I.The role of Stat5a and Stat5b in signaling by IL-2 family cytokines.Human intestinal epithelial cells express functional cytokine receptors sharing the common gamma c chain of the interleukin 2 receptorActivation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.Cellular signalling pathways: new targets in leukaemia therapy.Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.A human class II MHC-derived peptide antagonizes phosphatidylinositol 3-kinase to block IL-2 signaling.Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.Activated Ki-Ras complements erythropoietin signaling in CTLL-2 cells, inducing tyrosine phosphorylation of a 160-kDa protein.Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines.The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus miceInvolvement of Fyn tyrosine kinase in progression of cytokinesis of B lymphocyte progenitorInterleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway.Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis.Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cellsInterleukin 2 and erythropoietin activate STAT5/MGF via distinct pathwaysJAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chainsStructural domains of interleukin-2 receptor beta critical for signal transduction: kinase association and nuclear complex-formation.Erythropoietin and interleukin-2 activate distinct JAK kinase family members.Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation.Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signallingInterleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck.Lyn is essential for fcgamma receptor III-mediated systemic anaphylaxis but not for the Arthus reaction.Involvement of tyrosine kinases in the induction of cyclo-oxygenase-2 in human endothelial cells.Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of paxillin and FAK.Signaling pathways mediating chemokine induction in keratinocytes by cathelicidin LL-37 and flagellin.Cytokine ReceptorsInterleukin 2 mediates p72 syk activation in peripheral blood lymphocytes
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Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Functional coupling of the src ...... n cytokine signal transduction
@ast
Functional coupling of the src ...... n cytokine signal transduction
@en
type
label
Functional coupling of the src ...... n cytokine signal transduction
@ast
Functional coupling of the src ...... n cytokine signal transduction
@en
prefLabel
Functional coupling of the src ...... n cytokine signal transduction
@ast
Functional coupling of the src ...... n cytokine signal transduction
@en
P2093
P2860
P356
P1476
Functional coupling of the src ...... n cytokine signal transduction
@en
P2093
Hatakeyama M
Kobayashi N
Miyazaki T
Perlmutter RM
Taniguchi T
P2860
P304
P356
10.1073/PNAS.90.9.4201
P407
P577
1993-05-01T00:00:00Z