CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein
about
Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2)New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer.Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein.Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity.Clinical use of topoisomerase I inhibitors in anticancer treatment.DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity.Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application.Determinants of CPT-11 and SN-38 activities in human lung cancer cellsSensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.Recent development on naphthoquinone derivatives and their therapeutic applications as anticancer agents.Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells.Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines.MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer.Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells.MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids.Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors.Salvage treatment with topotecan in patients with irinotecan-refractory small cell lung cancer.Effect of hesperidin on the pharmacokinetics of CPT-11 and its active metabolite SN-38 by regulating hepatic Mrp2 in rats.
P2860
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P2860
CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
CPT-11 sensitivity in relation ...... resistance-associated protein
@ast
CPT-11 sensitivity in relation ...... resistance-associated protein
@en
type
label
CPT-11 sensitivity in relation ...... resistance-associated protein
@ast
CPT-11 sensitivity in relation ...... resistance-associated protein
@en
prefLabel
CPT-11 sensitivity in relation ...... resistance-associated protein
@ast
CPT-11 sensitivity in relation ...... resistance-associated protein
@en
P2093
P2860
P356
P1476
CPT-11 sensitivity in relation ...... resistance-associated protein
@en
P2093
G Giaccone
H M Pinedo
J van Ark-Otte
T M Hulscher
W J Jansen
P2860
P2888
P304
P356
10.1038/BJC.1998.58
P407
P577
1998-01-01T00:00:00Z