The current status of camptothecin analogues as antitumor agents.
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Immunodetection of human topoisomerase I-DNA covalent complexesCaspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosisThe role of checkpoint kinase 1 in sensitivity to topoisomerase I poisonsComparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cellsA weekly regimen of cisplatin, paclitaxel and topotecan with granulocyte-colony stimulating factor support for patients with extensive disease small cell lung cancer: a phase II studySupramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer CellsA Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignanciesClinical presentation, diagnosis, and pharmacotherapy of patients with primary brain tumors.DOSY NMR and MALDI-TOF evidence of covalent binding the DNA duplex by trimethylammonium salts of topotecan upon near UV irradiation.Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant gliomaA novel trial of topotecan, ifosfamide, and carboplatin (TIC) in children with recurrent solid tumors.Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administrationThe bioavailability of oral GI147211 (GG211), a new topoisomerase I inhibitorA phase I clinical and pharmacokinetic study of the new topoisomerase inhibitor GI147211 given as a 72-h continuous infusion.A review of the pharmacology and clinical activity of new chemotherapy agents for the treatment of colorectal cancer.Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sitesDesign and synthesis of new 7-(N-substituted-methyl)-camptothecin derivatives as potent cytotoxic agents.Novel chemotherapeutic agents for the treatment of brain cancer.SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I.Medicinal plants and cancer chemoprevention.Irinotecan and oxaliplatin: an overview of the novel chemotherapeutic options for the treatment of advanced colorectal cancer.Molecular and cytotoxic effects of camptothecin, a topoisomerase I inhibitor, on trypanosomes and LeishmaniaHigh antimetastatic efficacy of MEN4901/T-0128, a novel camptothecin carboxymethyldextran conjugatePerspectives on biologically active camptothecin derivatives.Prevention of K-Ras- and Pten-mediated intravaginal tumors by treatment with camptothecin-loaded PLGA nanoparticles.Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells.In-vitro Cellular Uptake and Transport Study of 9-Nitrocamptothecin PLGA Nanoparticles Across Caco-2 Cell Monolayer ModelHigh-content screening of human primary muscle satellite cells for new therapies for muscular atrophy/dystrophyDesign and synthesis of novel spin-labeled camptothecin derivatives as potent cytotoxic agentsTopotecan synergizes with CHEK1 (CHK1) inhibitor to induce apoptosis in ovarian cancer cells.Novel chemotherapeutic agents for the treatment of glioblastoma multiforme.Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.Metabolic conversion of methoxymorpholinyl doxorubicin: from a DNA strand breaker to a DNA cross-linkerSuccessful local regional therapy with topotecan of intraperitoneally growing human ovarian carcinoma xenograftsVariation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity.Local delivery of antineoplastic agents by controlled-release polymers for the treatment of malignant brain tumours.Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line.Determinants of CPT-11 and SN-38 activities in human lung cancer cellsCPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated proteinA small molecule screen identifies in vivo modulators of peripheral nerve regeneration in zebrafish.
P2860
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P2860
The current status of camptothecin analogues as antitumor agents.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
The current status of camptothecin analogues as antitumor agents.
@en
type
label
The current status of camptothecin analogues as antitumor agents.
@en
prefLabel
The current status of camptothecin analogues as antitumor agents.
@en
P2093
P356
P1476
The current status of camptothecin analogues as antitumor agents.
@en
P2093
E K Rowinsky
R C Donehower
W J Slichenmyer
P304
P356
10.1093/JNCI/85.4.271
P407
P577
1993-02-01T00:00:00Z