Distinct populations of HCN pacemaker channels produce voltage-dependent and voltage-independent currents.
about
Calcium-dependent binding of HCN1 channel protein to hair cell stereociliary tip link protein protocadherin 15 CD3HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2Asymmetric divergence in structure and function of HCN channel duplicates in Ciona intestinalis.State-dependent and site-directed photodynamic transformation of HCN2 channel by singlet oxygencAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.Population diversity and function of hyperpolarization-activated current in olfactory bulb mitral cells.Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.Coupling of voltage-sensors to the channel pore: a comparative viewActivation of Ih and TTX-sensitive sodium current at subthreshold voltages during CA1 pyramidal neuron firing.Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6.Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate.Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP.Intracellular Mg2+ is a voltage-dependent pore blocker of HCN channels.Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate.Connecting alveolate cell biology with trophic ecology in the marine plankton using the ciliate Favella as a model.Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice.In vitro characterization of HCN channel kinetics and frequency dependence in myocytes predicts biological pacemaker functionality.Functional characterization of hyperpolarization-activated cyclic nucleotide-gated channels in rat pancreatic beta cells.A leucine zipper motif essential for gating of hyperpolarization-activated channels.Ion binding in the open HCN pacemaker channel pore: fast mechanisms to shape "slow" channels.Stress Impairs Prefrontal Cortical Function via D1 Dopamine Receptor Interactions With Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels.Dual stretch responses of mHCN2 pacemaker channels: accelerated activation, accelerated deactivation.Hyperpolarisation-activated cyclic nucleotide-gated channels regulate the spontaneous firing rate of olfactory receptor neurons and affect glomerular formation in mice.Alanine scanning of the S6 segment reveals a unique and cAMP-sensitive association between the pore and voltage-dependent opening in HCN channels.HCN2 channels: a permanent open state and conductance changes.Kir2.1 channels set two levels of resting membrane potential with inward rectification.Hyperpolarization-activated currents are differentially expressed in mice brainstem auditory nuclei.Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus.Properties and functional implications of I (h) in hippocampal area CA3 interneurons.Tryptophan-scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation.
P2860
Q28580932-3055C91D-CA11-442F-867C-DAC749EF676DQ28584355-C8691F2E-F042-4921-B618-9BDA57EE5419Q34469554-EE3721AE-DF7A-473F-B2D1-3391D09C5D35Q35148179-7CEDC7D9-5C68-443E-84DF-CCC258A49E7EQ35199062-BEC0E0DD-185F-4215-BF6C-4CE7CB534B34Q35551369-944ED016-2167-4C6D-A310-47B85BCAC065Q35995928-0960A2B3-E75F-4210-95D6-8300ACA48F7AQ36121859-D0A5DC70-516D-4DE9-8E16-29947BFF870CQ36205040-4EFEF3E4-BA19-44D9-B5F8-0C67ED1A0A51Q36295815-D9B36C2E-DC8B-40D7-9DBB-28C2B45FC899Q36353443-4A952991-7F92-4366-B367-F191E7BF2177Q36487302-FD2DEA90-47D6-4523-AA82-29F87AA8CA71Q36842363-A0199338-4D5F-4B10-9138-AD228AA53C13Q37276622-EFF59BCB-4D02-458F-812F-3AF1056CEAE7Q38231296-C6CCB148-92CE-44B3-BD22-614F9AD2A390Q39426655-EF5CD04D-E52F-4A67-95A9-82F3F27537B4Q40007335-F494010B-67ED-4F24-B431-46D36FDF617EQ40760593-94AEEE21-5205-4437-A622-7A3CF262CC8CQ41755565-857998CE-1971-4030-A3EE-567C79BA0A90Q41907791-120E4E48-B42C-453A-B3A3-3782ED206DE7Q41935751-6EB7D686-1F82-4B32-9698-ABB42FB16BEBQ41947639-732D63E2-456F-45CB-AD8C-8F1A7462807AQ42519313-BE6EE65B-3709-42A6-B8DC-DA46A3F45508Q42614326-0211F79E-1ECD-41BB-A2BA-54AACCC4DFDEQ42692929-CDF4ADF2-8040-41AB-9E56-2AACB240A65CQ48340157-58AE3C22-8B1E-493B-8EAC-35822B386C14Q48444381-7C02600F-45EE-44F6-84F7-7255CB27F433Q48544059-7FAAD0B7-4A7D-4D1B-9A75-8618807FE168Q48884138-6E0AB2BF-D241-4BEF-ADCA-13B23CD508C7Q50641169-31F28217-A687-4EC1-AAAF-8DE05C445CC0
P2860
Distinct populations of HCN pacemaker channels produce voltage-dependent and voltage-independent currents.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Distinct populations of HCN pa ...... voltage-independent currents.
@ast
Distinct populations of HCN pa ...... voltage-independent currents.
@en
type
label
Distinct populations of HCN pa ...... voltage-independent currents.
@ast
Distinct populations of HCN pa ...... voltage-independent currents.
@en
prefLabel
Distinct populations of HCN pa ...... voltage-independent currents.
@ast
Distinct populations of HCN pa ...... voltage-independent currents.
@en
P2860
P356
P1476
Distinct populations of HCN pa ...... voltage-independent currents.
@en
P2093
Catherine Proenza
Gary Yellen
P2860
P304
P356
10.1085/JGP.200509389
P577
2006-02-01T00:00:00Z