Comparative analysis of p73 and p53 regulation and effector functions.
about
DeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkASpatiotemporal switch from DeltaNp73 to TAp73 isoforms during nephrogenesis: impact on differentiation gene expressionFunction of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in micePhysical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function.Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoterRole of p73 in malignancy: tumor suppressor or oncogene?Novel ARF/p53-independent senescence pathways in cancer repression.MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 functionRegulatory feedback loop between TP73 and TRIM32.Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53.The human p73 promoter: characterization and identification of functional E2F binding sites.Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.Restoration of wild-type p53 in drug-resistant mouse breast cancer cells leads to differential gene expression, but is not sufficient to overcome the malignant phenotype.p73 expression is regulated by RNPC1, a target of the p53 family, via mRNA stabilityThe C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73.DeltaNp73beta is active in transactivation and growth suppression.p73 plays a role in erythroid differentiation through GATA1 induction.p73alpha is a candidate effector in the p53 independent apoptosis pathway of cisplatin damaged primary murine colonocytes.Overexpression of p73 causes apoptosis in vascular smooth muscle cells.Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells.Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax.MDM2 and MDMX can interact differently with ARF and members of the p53 family
P2860
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P2860
Comparative analysis of p73 and p53 regulation and effector functions.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Comparative analysis of p73 and p53 regulation and effector functions.
@ast
Comparative analysis of p73 and p53 regulation and effector functions.
@en
type
label
Comparative analysis of p73 and p53 regulation and effector functions.
@ast
Comparative analysis of p73 and p53 regulation and effector functions.
@en
prefLabel
Comparative analysis of p73 and p53 regulation and effector functions.
@ast
Comparative analysis of p73 and p53 regulation and effector functions.
@en
P2093
P2860
P356
P1476
Comparative analysis of p73 and p53 regulation and effector functions.
@en
P2093
P2860
P304
P356
10.1083/JCB.147.4.823
P407
P577
1999-11-01T00:00:00Z